TAF5 and TAF7

Number of citations of the paper that reports this interaction (PubMedID 14580349)
21

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		TAF5	TAF7
Description		TATA-box binding protein associated factor 5	TATA-box binding protein associated factor 7
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Factor TFIID Complex Nucleolus Actin Cytoskeleton Transcription Factor TFTC Complex	Nucleoplasm Transcription Regulator Complex Transcription Factor TFIID Complex Cytoplasm Transcription Factor TFTC Complex MLL1 Complex
	Molecular Function	Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Identical Protein Binding	Transcription Cis-regulatory Region Binding TFIIH-class Transcription Factor Complex Binding Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity Histone Acetyltransferase Binding Vitamin D Receptor Binding Thyroid Hormone Receptor Binding Protein Heterodimerization Activity H3K27me3 Modified Histone Binding P-TEFb Complex Binding
	Biological Process	DNA-templated Transcription, Initiation Transcription Initiation From RNA Polymerase II Promoter	Negative Regulation Of Transcription By RNA Polymerase II Spermine Transport DNA-templated Transcription, Initiation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Protein Kinase Activity Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Histone Acetylation Negative Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of MHC Class II Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Negative Regulation Of Histone H4 Acetylation
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Height ( 31562340) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 25056061 23974872)	Mean platelet volume ( 32888494 27863252) Refractive error ( 32231278)
Interacting Genes		16 interacting genes: CPSF1 GTF2F2 H3-4 TAF1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF6 TAF7 TAF8 TAF9 TBP UBE2I	28 interacting genes: AHR CDK7 CDK9 CPSF1 FAU GATA1 H3-4 HSF1 IKBKG MAP1LC3B OGT RBM6 SETD7 TAF1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF5 TAF6 TAF8 TAF9 TRIM22 TRIM24 YWHAE ZSCAN1
Entrez ID		6877	6879
HPRD ID		11876	07196
Ensembl ID		ENSG00000148835	ENSG00000178913
Uniprot IDs		Q15542	Q15545
PDB IDs		2NXP 6F3T 6MZC 6MZD 6MZL 6MZM	4RGW 5FUR 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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