XCL2 and CXCL17

Number of citations of the paper that reports this interaction (PubMedID 28381538)
37

Data Source:
BioGRID (pull down)

		XCL2	CXCL17
Description		X-C motif chemokine ligand 2	C-X-C motif chemokine ligand 17
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Space
	Molecular Function	Protein Binding Chemokine Activity CCR Chemokine Receptor Binding	Protein Binding
	Biological Process	Monocyte Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Blood Circulation Positive Regulation Of T Cell Chemotaxis Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Angiogenesis Positive Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Macrophage Chemotaxis Cell Differentiation Macrophage Chemotaxis Negative Regulation Of Inflammatory Response Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Monocyte Chemotaxis
Pathways		Chemokine receptors bind chemokines G alpha (q) signalling events
Drugs
Diseases
GWAS		Emphysema imaging phenotypes ( 26030696) Lung cancer ( 28604730) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		19 interacting genes: CCL2 CCL20 CCL21 CCL26 CCL28 CCL5 CCL7 CCL8 CXCL12 CXCL17 CXCL2 CXCL3 CXCL5 KRTAP1-3 KRTAP10-9 NOTCH2NLA PF4 PF4V1 XCR1	16 interacting genes: CCL13 CCL2 CCL20 CCL21 CCL25 CCL26 CCL28 CCL5 CCL8 CXCL10 CXCL12 CXCL14 CXCL9 PF4 XCL1 XCL2
Entrez ID		6846	284340
HPRD ID		05317	18264
Ensembl ID		ENSG00000143185	ENSG00000189377
Uniprot IDs		Q9UBD3	Q6UXB2
PDB IDs
Enriched GO Terms of Interacting Partners?
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