SUPT4H1 and NSG2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		SUPT4H1	NSG2
Description		SPT4 homolog, DSIF elongation factor subunit	neuronal vesicle trafficking associated 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm DSIF Complex	Endosome Early Endosome Late Endosome Golgi Apparatus Integral Component Of Membrane Dendrite Cytoplasmic Vesicle Membrane Early Endosome Membrane Multivesicular Body Membrane Trans-Golgi Network Membrane Lysosomal Lumen Golgi Cis Cisterna Membrane
	Molecular Function	RNA Polymerase II Complex Binding Protein Binding Zinc Ion Binding Protein Heterodimerization Activity	Protein Binding Clathrin Light Chain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription, DNA-templated Transcription Elongation From RNA Polymerase II Promoter MRNA Processing Negative Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II	Dopamine Receptor Signaling Pathway Endosomal Transport Clathrin Coat Assembly
Pathways		Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Eosinophil percentage of white cells ( 32888494) Mental health study participation (completed survey) ( 31263887) Refractive error ( 32231278)	Alzheimer's disease ( 33074286) Blond vs. brown/black hair color ( 30531825) Diffusing capacity of carbon monoxide ( 30694715) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		12 interacting genes: ANXA5 APP EWSR1 HTATSF1 LRIF1 LRRK2 MFHAS1 NSG2 PDLIM1 SMARCA2 SUPT5H XRCC5	17 interacting genes: ANKRD46 APOC1 C3orf52 CLEC7A HCFC1R1 NDUFA2 RIF1 RPS27 RRH SERPINH1 SLC35F6 STX18 SUPT4H1 TNNT1 TSPAN6 UCHL3 ZNF768
Entrez ID		6827	51617
HPRD ID		16026	13664
Ensembl ID		ENSG00000213246	ENSG00000170091
Uniprot IDs		P63272	Q9Y328
PDB IDs		3H7H 5OIK 6GMH 6GML 6TED
Enriched GO Terms of Interacting Partners?
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