SSB and HMGA1

Number of citations of the paper that reports this interaction (PubMedID 18850631)
12

Data Source:
BioGRID (far western blotting)

		SSB	HMGA1
Description		small RNA binding exonuclease protection factor La	high mobility group AT-hook 1
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GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Cytoplasm Ribonucleoprotein Complex	Nucleus Nucleoplasm Transcription Regulator Complex Cytosol Focal Adhesion Senescence-associated Heterochromatin Focus RNA Polymerase II Transcription Regulator Complex
	Molecular Function	TRNA Binding RNA Binding MRNA Binding Protein Binding Poly(U) RNA Binding Sequence-specific MRNA Binding	Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Minor Groove Of Adenine-thymine-rich DNA Binding Chromatin Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Enzyme Binding Nuclear Receptor Coactivator Activity Structural Constituent Of Chromatin Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Retinoid X Receptor Binding
	Biological Process	TRNA 5'-leader Removal TRNA Modification TRNA Export From Nucleus TRNA Processing Histone MRNA Metabolic Process TRNA 3'-end Processing Nuclear Histone MRNA Catabolic Process IRES-dependent Viral Translational Initiation Protein Localization To Cytoplasmic Stress Granule	DNA Unwinding Involved In DNA Replication Nucleosome Disassembly Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Population Proliferation Response To Virus Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Oncogene-induced Cell Senescence Positive Regulation Of Cellular Senescence
Pathways		RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation	Integration of provirus 2-LTR circle formation Integration of viral DNA into host genomic DNA Autointegration results in viral DNA circles APOBEC3G mediated resistance to HIV-1 infection Vpr-mediated nuclear import of PICs Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS		Common carotid intima-media thickness in HIV infection ( 29206233) Fasting glucose change (long-term) ( 31263163) Glomerular filtration rate in diabetes ( 29703844)	Anthropometric traits ( 30166351) Anthropometric traits (multi-trait analysis) ( 30166351) Apolipoprotein A1 levels ( 32203549) Birth weight ( 31043758 27680694) Body mass index ( 26426971 28892062 20935630) Body shape index ( 34021172) Estimated glomerular filtration rate ( 31152163) FEV1 ( 30804560) Hand grip strength ( 29691431) Height ( 21998595 34054925 20881960 25282103 25429064 19396169 19343178 19893584 23563607 31562340 18391951 20397748 20189936) Hemoglobin levels ( 32327693) Hip circumference adjusted for BMI ( 34021172 25673412) Lung function (FVC) ( 30804560) Lymphocyte counts ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolic syndrome ( 31589552) Myeloproliferative neoplasms ( 33057200) Offspring birth weight ( 31043758) Plateletcrit ( 32888494) Regular attendance at a gym or sports club ( 29970889) Systolic blood pressure ( 30578418) Tonsillectomy ( 27182965 28928442) Triglyceride levels ( 32203549) Type 2 diabetes ( 32499647) Type 2 diabetes (adjusted for BMI) ( 30297969) Uterine fibroids ( 31649266) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 28552196 34021172 25673412 28448500) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for body mass index ( 25673412) Weight ( 34054925)
Interacting Genes		13 interacting genes: APP CDC42 CSNK2A1 CSNK2B GZMH HMGA1 IL7R NAT8 NCL OGT PTEN SPIB SPP1	64 interacting genes: ANXA1 ANXA2 APEX1 APP ATF2 CDK1 CEBPB CREBBP CSNK2A1 CSNK2A2 CWC27 DNAJC8 EIF2S2 ELF1 EWSR1 GTF2F2 HEMGN HIPK2 HMGB1 HMGB2 HMGB3 HNRNPA1 HNRNPAB HNRNPD HNRNPDL HNRNPL HPF1 HSPA1A IRF1 JUN KAT2B METAP2 NCL NFKB1 NFYA NPM1 OLA1 ORC6 PA2G4 PARP1 PCBP1 PCBP2 POU2F1 POU2F2 POU3F1 PPARG PPP1R8 PRKCA PRMT6 PSIP1 PTBP1 RARA RARG RCC1 RN7SK RNF4 RXRA SP1 SRF SRPK2 SSB SUFU SYNCRIP UPF2
Entrez ID		6741	3159
HPRD ID		00168	02829
Ensembl ID		ENSG00000138385	ENSG00000137309
Uniprot IDs		P05455	P17096 Q5T6U8
PDB IDs		1OWX 1S79 1S7A 1YTY 1ZH5 2VOD 2VON 2VOO 2VOP	2EZD 2EZE 2EZF 2EZG
Enriched GO Terms of Interacting Partners?
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