SP1 and SP4

  • Number of citations of the paper that reports this interaction (PubMedID 7559627)
  • 40
  • Data Source:
  • HPRD (in vitro)

SP1

SP4

Description Sp1 transcription factor Sp4 transcription factor
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute lymphoblastic leukemia (childhood) ( 29348612)
  • Age at first sexual intercourse ( 34211149)
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Apolipoprotein B levels ( 32203549)
  • Aspartate aminotransferase levels in non-alcoholic fatty liver disease ( 31311600)
  • Bipolar disorder ( 31043756)
  • General cognitive ability ( 29844566)
  • LDL cholesterol levels ( 32203549)
  • Major depressive disorder ( 20125088)
  • Major depressive disorder (broad) ( 20038947)
  • Multiple cancers (lung cancer, gastric cancer, and squamous cell carcinoma) ( 23103227)
  • Multisite chronic pain ( 33830993 31194737)
  • Plateletcrit ( 32888494)
  • Schizophrenia ( 30285260)
  • Temporomandibular joint disorder ( 28081371)
Interacting Genes 152 interacting genes: AATF AHR AKT1 AR ARHGAP21 ARNT ATF7IP ATF7IP2 BCL11B BCL6 BCOR BRCA1 CASP3 CASP6 CASP7 CBX5 CCNA1 CCNA2 CCND1 CD2 CDK1 CDK2 CEBPB CSNK2A1 CTCFL CTNNB1 DDX5 DROSHA E2F1 E2F2 E2F3 EGR1 ELF1 ENDOU EP300 ESR1 ESR2 ESRRA ESRRB ESRRG ETS1 GABPA GATA1 GATA3 GATA4 GRIN1 HBZ HCFC1 HDAC1 HDAC2 HIF1A HINT1 HLTF HMGA1 HNF4A HNRNPA1 HOXC11 HSPA8 HTT IL1B JUN KIF1A KLF10 KLF4 KLF6 LDB1 LMO2 MAPK1 MAPK3 MAPK8 MBD1 MEF2C MEF2D MIER1 MIS18BP1 MSX1 MTREX MYC MYCN MYOD1 MYOG NAP1L1 NCOR1 NCOR2 NEDD4L NEPRO NFKB1 NFKB2 NFYA NFYB NFYC NKX3-1 NOS3 NPM1 NR2F1 NR5A1 NUP62 OGT PARP1 PER3 PML POGZ POU2F1 PPIG PPP1R13L PRKCZ PRKDC PSIP1 PSMC5 PURA RAPGEF3 RARA RB1 RBBP4 RBL1 REG1A REL RELA RNF4 RORA RXRA SENP6 SF3A1 SHC1 SMAD2 SMAD3 SMAD4 SMARCC1 SMARCC2 SOX10 SOX8 SP3 SP4 SREBF1 SREBF2 SRF SUB1 SUMO2 TAF4 TAL1 TBP TLX3 TP53 TP73 TPI1 USP39 VEGFA VHL YY1 ZBTB16 ZBTB2 ZBTB7A 35 interacting genes: ADAM15 AP1M1 ATXN7L1 BANP CIB3 COL8A1 E2F1 ELK3 FOXP2 GTF2A1 HIVEP1 HYPK ITGB8 LMO3 LNX1 MCRS1 NFYC NKX3-1 NRF1 PELI2 PNKP POGZ POU2F1 PRR20A PRR20B PRR20C PRR20D PRR20E PRSS59P SERF2 SP1 SPANXN2 SPANXN3 VEZF1 ZBTB7A
Entrez ID 6667 6671
HPRD ID 01796 02764
Ensembl ID ENSG00000185591 ENSG00000105866
Uniprot IDs P08047 A0A3B3IRW4 Q02446 Q32M51
PDB IDs 1SP1 1SP2 1VA1 1VA2 1VA3 6PV0 6PV1 6PV2 6PV3 6UCO 6UCP
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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