FUNDC2 and USP13

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FUNDC2	USP13
Description		FUN14 domain containing 2	ubiquitin specific peptidase 13
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Integral Component Of Mitochondrial Outer Membrane	Nucleus Nucleoplasm Cytosol
	Molecular Function	Protein Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding Ubiquitin-like Protein Ligase Binding Chaperone Binding Proteasome Binding BAT3 Complex Binding Lys48-specific Deubiquitinase Activity
	Biological Process	Autophagy Of Mitochondrion	Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Autophagy Cell Population Proliferation Regulation Of Autophagy Protein Deubiquitination Melanocyte Differentiation Protein K29-linked Deubiquitination Protein K6-linked Deubiquitination Protein Stabilization Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Positive Regulation Of ERAD Pathway Maintenance Of Unfolded Protein Involved In ERAD Pathway
Pathways			Ub-specific processing proteases Regulation of PTEN stability and activity
Drugs
Diseases
GWAS
Interacting Genes		38 interacting genes: AQP6 ARL13B ARL15 ASCC2 ATP13A2 CD79A CIDEB COX20 CRB3 CYB5R3 DRC3 EBP EIF6 EVI2B FCER1G FGF14 GPR152 KCNJ6 KIR2DL3 MFSD14B MGST3 NACA NSF NUDT21 REEP4 RETREG3 RGS1 SAT1 SDR16C5 SLC10A6 SLC16A10 SLC66A2 STOM SYT2 TMEM154 TMX2 TP53I3 USP13	24 interacting genes: AMFR BAG6 CLK3 DAZAP2 DVL1 FNBP1L FUNDC2 GPR160 HSP90AA1 LAPTM5 MCL1 MDC1 MRPL20 MYO15A S100A9 SIAH2 SPRR2C SYCP2 TRA2B TRIM55 TRIM63 UBC UBL4A UIMC1
Entrez ID		65991	8975
HPRD ID		06586	04666
Ensembl ID		ENSG00000165775	ENSG00000058056
Uniprot IDs		Q9BWH2	A0A0A6YZ17 Q92995
PDB IDs			2L80 2LBC
Enriched GO Terms of Interacting Partners?
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