SLIT1 and TRIM42

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLIT1	TRIM42
Description		slit guidance ligand 1	tripartite motif containing 42
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space
	Molecular Function	Calcium Ion Binding Protein Binding Heparin Binding Roundabout Binding	Protein Binding Zinc Ion Binding
	Biological Process	Nuclear Migration Axon Guidance Motor Neuron Axon Guidance Chemorepulsion Involved In Embryonic Olfactory Bulb Interneuron Precursor Migration Retinal Ganglion Cell Axon Guidance Dorsal/ventral Axon Guidance Axon Extension Involved In Axon Guidance Forebrain Morphogenesis Negative Chemotaxis Negative Regulation Of Synapse Assembly
Pathways		Netrin-1 signaling Signaling by ROBO receptors Regulation of commissural axon pathfinding by SLIT and ROBO Regulation of cortical dendrite branching Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		Bipolar disorder ( 28115744) Diastolic blood pressure (alcohol consumption interaction) ( 24376456) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Obesity-related traits ( 23251661)	Bipolar disorder (body mass index interaction) ( 24322204) Refractive astigmatism ( 25367360)
Interacting Genes		17 interacting genes: ADAMTSL4 ATN1 CHRDL2 CYSRT1 FHL5 FXR1 GPC1 HOXA1 KRTAP1-1 KRTAP10-8 KRTAP13-2 KRTAP13-3 MEOX2 MTNR1A ROBO1 TRIM42 ZNF620	145 interacting genes: ADAMTSL4 AQP1 ARMC7 ARNT2 ARRDC3 ATG9A AXIN1 BACH2 BEX2 C1orf109 CARD9 CATSPER1 CBY2 CCDC120 CCDC24 CCDC33 CDCA7L CEP70 CERK CHCHD2 CHRD CREB5 CYSRT1 EFEMP2 EFHC2 EMD FAM124B FAM90A1 FBLN1 FCHO1 FNDC3B GLI1 GLRX3 GLYCTK GNE GOLGA2 GUCD1 HOXA1 HOXC8 HSD3B7 IGFN1 IHO1 IKZF3 IL16 IQUB KCTD9 KLHL38 KPRP KRT13 KRT15 KRT34 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-2 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-7 KRTAP9-3 L3MBTL2 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LNX1 LONRF1 LZTS2 MAGOHB MAPKBP1 MEIS2 MEOX2 MFAP1 MGAT5B MID2 MTUS2 MVP NBPF19 NEK8 NOTCH2NLA OTX1 PCSK5 PHLDA1 PLSCR1 PLSCR4 PNMA1 POU4F2 PRKAB2 PROP1 PSMA1 PSMD9 PTGER3 R3HDM2 RAMAC RCOR3 RUNX1T1 SCNM1 SHFL SLIT1 SMARCC1 SMCP SPAG8 SSX2IP STK16 TASOR2 TCAF1 TFAP2D TLX3 TMEM150A TRAF1 TRAF2 TRAPPC2B TRIM23 TRIM27 TXNDC5 VGLL3 VPS37A VWC2L YIPF3 YWHAQ YY1 ZBTB1 ZNF330 ZNF414
Entrez ID		6585	287015
HPRD ID		04773	15559
Ensembl ID		ENSG00000187122	ENSG00000155890
Uniprot IDs		A6H8V1 O75093	Q8IWZ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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