SLC6A9 and GABRR1

Number of citations of the paper that reports this interaction (PubMedID 10625616)
10

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		SLC6A9	GABRR1
Description		solute carrier family 6 member 9	gamma-aminobutyric acid type A receptor subunit rho1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Postsynaptic Density Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Integral Component Of Synaptic Vesicle Membrane Dense Core Granule Hippocampal Mossy Fiber To CA3 Synapse Parallel Fiber To Purkinje Cell Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane	Plasma Membrane Integral Component Of Plasma Membrane Chloride Channel Complex Neuron Projection Synapse Postsynaptic Membrane Glutamatergic Synapse GABA-ergic Synapse GABA-A Receptor Complex
	Molecular Function	Glycine Transmembrane Transporter Activity Glycine:sodium Symporter Activity	GABA-A Receptor Activity Chloride Channel Activity Neurotransmitter Receptor Activity Ligand-gated Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Neurotransmitter Transport Glycine Transport Sodium Ion Transmembrane Transport Positive Regulation Of Hemoglobin Biosynthetic Process Positive Regulation Of Heme Biosynthetic Process Transport Across Blood-brain Barrier Glycine Import Across Plasma Membrane Positive Regulation Of Iron Ion Transmembrane Transporter Activity Positive Regulation Of Iron Ion Import Across Plasma Membrane Negative Regulation Of NMDA Glutamate Receptor Activity	Signal Transduction Gamma-aminobutyric Acid Signaling Pathway Chemical Synaptic Transmission Ion Transmembrane Transport Regulation Of Membrane Potential Nervous System Process Regulation Of Postsynaptic Membrane Potential Regulation Of Presynaptic Membrane Potential Chloride Transmembrane Transport
Pathways		Na+/Cl- dependent neurotransmitter transporters	GABA receptor activation
Drugs			Lindane Picrotoxin Fludiazepam
Diseases
GWAS		Attention deficit hyperactivity disorder or cannabis use ( 30610198) Autism spectrum disorder or schizophrenia ( 28540026) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 29403010 32888494) Refractive error ( 32231278)	Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Bipolar disorder and schizophrenia ( 20889312) Diabetic kidney disease in type 2 diabetes ( 29703844) Early diabetic kidney disease in type 2 diabetes ( 29703844) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472)
Interacting Genes		6 interacting genes: GABRR1 NAPA PPP2R3B PRKCA STX1A TP53BP1	10 interacting genes: CSNK2A1 GABRR2 MAP1B MAPK1 P2RX2 PRKACA PRKCA PRKG1 SLC6A9 SQSTM1
Entrez ID		6536	2569
HPRD ID		03010	15921
Ensembl ID		ENSG00000196517	ENSG00000146276
Uniprot IDs		B7Z3W8 B7Z589 P48067	P24046
PDB IDs
Enriched GO Terms of Interacting Partners?
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