SLC3A1 and SLC7A8

Number of citations of the paper that reports this interaction (PubMedID 10574970)
77

Data Source:
HPRD (in vivo)

		SLC3A1	SLC7A8
Description		solute carrier family 3 member 1	solute carrier family 7 member 8
Image
GO Annotations	Cellular Component	Vacuolar Membrane Plasma Membrane Integral Component Of Plasma Membrane Membrane Apical Plasma Membrane Brush Border Membrane Extracellular Exosome	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Microvillus Membrane
	Molecular Function	Catalytic Activity Protein Binding Amino Acid Transmembrane Transporter Activity Basic Amino Acid Transmembrane Transporter Activity L-cystine Transmembrane Transporter Activity Protein-containing Complex Binding Protein Heterodimerization Activity	Protein Binding Organic Cation Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity Glycine Transmembrane Transporter Activity L-leucine Transmembrane Transporter Activity Thyroid Hormone Transmembrane Transporter Activity Toxin Transmembrane Transporter Activity Peptide Antigen Binding
	Biological Process	Carbohydrate Metabolic Process Amino Acid Transport Gene Expression Basic Amino Acid Transport Aspartate Transmembrane Transport L-cystine Transport L-glutamate Transmembrane Transport Basic Amino Acid Transmembrane Transport	Amino Acid Transmembrane Transport Amino Acid Transport Response To Toxic Substance Organic Cation Transport Neutral Amino Acid Transport Glycine Transport Leucine Transport Tryptophan Transport Valine Transport Proline Transmembrane Transport Metal Ion Homeostasis Thyroid Hormone Transport Amino Acid Import Across Plasma Membrane Leucine Import Across Plasma Membrane Transport Across Blood-brain Barrier Toxin Transport L-leucine Import Across Plasma Membrane L-alanine Import Across Plasma Membrane
Pathways		Amino acid transport across the plasma membrane Defective SLC3A1 causes cystinuria (CSNU) Defective SLC7A9 causes cystinuria (CSNU)	Basigin interactions Amino acid transport across the plasma membrane
Drugs			Phenylalanine Alanine
Diseases
GWAS		antipsychotic drug dosage in schizophrenia or schizoaffective disorder ( 26821981) Refractive error ( 32231278)
Interacting Genes		2 interacting genes: NPTX1 SLC7A8	26 interacting genes: ABHD16A AGPAT4 AQP6 COMT DERL1 FXYD6-FXYD2 MFF MFSD3 NDUFA3 NINJ2 REEP4 SIGLEC5 SLC25A46 SLC30A2 SLC3A1 SLC3A2 SMPD2 SNORC SYCE1L SYNJ2BP TMEM14B TMEM208 TMEM60 TMEM65 YIPF1 YIPF6
Entrez ID		6519	23428
HPRD ID		00090	11971
Ensembl ID		ENSG00000138079	ENSG00000092068
Uniprot IDs		A0A0S2Z4E1 B8ZZK1 Q07837	Q53EM9 Q9UHI5
PDB IDs		6LI9 6LID 6YUP 6YUZ	7CMH 7CMI
Enriched GO Terms of Interacting Partners?
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