MARCKSL1 and DCTN2

Number of citations of the paper that reports this interaction (PubMedID 10827182)
14

Data Source:
BioGRID (biochemical)
HPRD (in vitro, in vivo)

		MARCKSL1	DCTN2
Description		MARCKS like 1	dynactin subunit 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Extracellular Exosome	Kinetochore Cytoplasm Centrosome Cytosol Dynactin Complex Microtubule Membrane Dynein Complex Growth Cone Vesicle Extracellular Exosome
	Molecular Function	Protein Binding Calmodulin Binding Actin Filament Binding	Protein Binding Protein Kinase Binding Spectrin Binding Identical Protein Binding
	Biological Process	Actin Filament Organization Central Nervous System Development Positive Regulation Of Cell Population Proliferation	Mitotic Spindle Organization Mitotic Metaphase Plate Congression Melanosome Transport Protein Localization To Centrosome
Pathways			MHC class II antigen presentation Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic AURKA Activation by TPX2
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545)
Interacting Genes		3 interacting genes: BRCA1 CDC42 DCTN2	39 interacting genes: ABI2 BICD1 BICD2 BLOC1S1 BLOC1S2 BLOC1S6 CALM1 CCDC172 CENPH CEP44 COG3 DISC1 EGFR FXR1 FXR2 GADD45A GADD45G GNAO1 GOLM1 GRB2 GSK3B HAUS1 HGS KIFC3 KPNA2 MAPK6 MAPRE3 MARCKSL1 OGT PAFAH1B1 RABGEF1 RINT1 RPGR SHANK3 SMARCD1 TSC1 TXLNB USHBP1 ZW10
Entrez ID		65108	10540
HPRD ID		04247	09568
Ensembl ID		ENSG00000175130	ENSG00000175203
Uniprot IDs		P49006	A0A384MDU9 A8K8J9 B3KTX4 Q13561 V9HW58
PDB IDs
Enriched GO Terms of Interacting Partners?
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