SLC1A5 and APOL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC1A5	APOL3
Description		solute carrier family 1 member 5	apolipoprotein L3
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Membrane Integral Component Of Membrane Melanosome Extracellular Exosome	Extracellular Region Cytoplasm Membrane
	Molecular Function	Virus Receptor Activity Protein Binding Amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transmembrane Transporter Activity L-aspartate Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity L-serine Transmembrane Transporter Activity Symporter Activity Signaling Receptor Activity Metal Ion Binding	Lipid Transporter Activity Lipid Binding
	Biological Process	Amino Acid Transport Glutamine Transport Glutamine Secretion Neutral Amino Acid Transport L-serine Transport Viral Entry Into Host Cell Protein Homotrimerization L-aspartate Import Across Plasma Membrane Transport Across Blood-brain Barrier L-glutamine Import Across Plasma Membrane	Lipid Transport Inflammatory Response Lipoprotein Metabolic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways		Amino acid transport across the plasma membrane RAC1 GTPase cycle RHOQ GTPase cycle RHOH GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle
Drugs		Asparagine Fluciclovine (18F)
Diseases
GWAS		Conjunctival UV autofluorescence (CUVAF) ( 25590795) Metabolite levels ( 23823483)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin) ( 23648065) Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Estimated glomerular filtration rate ( 31152163) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Serum alkaline phosphatase levels ( 33547301) Total intracranial volume ( 31530798)
Interacting Genes		5 interacting genes: APOL3 ERVW-1 PLP1 TBC1D17 TRARG1	28 interacting genes: ELOVL4 FATE1 FXYD6-FXYD2 GJA8 GJB1 GJB5 GJC1 GPR152 GPRC5D HAS3 IL7R LHFPL5 LINC00839 LRRC25 MFSD6 NCALD PMP22 RNF19B SGCB SLC16A2 SLC1A5 SLC7A14 STX1A TIMMDC1 TMEM167B TMEM237 TMEM52B TNFRSF10D
Entrez ID		6510	80833
HPRD ID		00173	06264
Ensembl ID		ENSG00000105281	ENSG00000128284
Uniprot IDs		Q15758 Q59ES3	A0A024R1G6 O95236
PDB IDs		5LLM 5LLU 5LM4 5MJU 6GCT 6MP6 6MPB 6RVX 6RVY
Enriched GO Terms of Interacting Partners?
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