CDCP1 and ST14

Number of citations of the paper that reports this interaction (PubMedID 16007225)
65

Data Source:
HPRD (in vivo)

		CDCP1	ST14
Description		CUB domain containing protein 1	ST14 transmembrane serine protease matriptase
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Membrane	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Extrinsic Component Of Plasma Membrane
	Molecular Function	Protein Binding	Serine-type Endopeptidase Activity Serine-type Peptidase Activity
	Biological Process		Neural Tube Closure Proteolysis Keratinocyte Differentiation Epithelial Cell Morphogenesis Involved In Placental Branching
Pathways			Formation of the cornified envelope Formation of the cornified envelope
Drugs			Urokinase Benzamidine Camostat
Diseases
GWAS		Acne (severe) ( 24927181) Blood protein levels ( 30072576) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Macular thickness ( 30535121) Metabolite levels ( 23823483) Statin-induced myopathy (severe) ( 31220337)	Adverse response to drug ( 30420678) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		7 interacting genes: CLK1 FYCO1 PLG PRKCD SDCBP SRC ST14	18 interacting genes: AKT1 APC CASP8 CDCP1 CDKN2C CHEK2 F2RL1 HGF NFRKB NOTCH2 PDGFC PHB PLAU RAD51 RGS16 SPINT1 STK11 TGFB1
Entrez ID		64866	6768
HPRD ID		16696	06005
Ensembl ID		ENSG00000163814	ENSG00000149418
Uniprot IDs		Q9H5V8	Q9Y5Y6
PDB IDs			1EAW 1EAX 2FMV 2GV6 2GV7 3BN9 3NCL 3NPS 3P8F 3P8G 3SO3 4IS5 4ISL 4ISN 4ISO 4JYT 4JZ1 4JZI 4O97 4O9V 4R0I 5LYO 6N4T 6T9T
Enriched GO Terms of Interacting Partners?
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