RUSF1 and PDCD1LG2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RUSF1	PDCD1LG2
Description		RUS family member 1	programmed cell death 1 ligand 2
Image		No pdb structure
GO Annotations	Cellular Component	Membrane Integral Component Of Membrane	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Endomembrane System Integral Component Of Membrane
	Molecular Function	Protein Binding	Molecular_function Protein Binding
	Biological Process		Adaptive Immune Response Immune Response Cell Surface Receptor Signaling Pathway T Cell Costimulation Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-10 Production Positive Regulation Of T Cell Proliferation Negative Regulation Of T Cell Proliferation Negative Regulation Of Activated T Cell Proliferation Cellular Response To Lipopolysaccharide
Pathways			PD-1 signaling
Drugs
Diseases
GWAS			Blood protein levels ( 30072576 29875488 28240269) Serum alkaline phosphatase levels ( 33339817)
Interacting Genes		53 interacting genes: AQP6 ARL6IP6 BIK C5orf46 CISD2 CMTM5 CREB3 CREB3L1 CREB3L3 DCTPP1 DGAT2L6 DHRSX EBP EHHADH ERGIC3 FAM209A FCER1G FFAR2 FKBP7 GJA8 GPR42 HSD17B13 IFNGR1 IL10RA ITGAM LHFPL5 LMNA MMGT1 MS4A4A ODF4 PDCD1LG2 PGRMC2 PSCA PVR RETREG3 RNF5 SCN3B SFXN3 SLC10A1 SLC10A6 SLC30A8 SLC35C2 SLC35E3 SPAG4 SSMEM1 TEX29 TMEM237 TMEM248 TMEM35A TMX2 UBE2I ZCCHC12 ZDHHC15	21 interacting genes: ATP6V0C ERMP1 EXOSC8 GALNT15 GPR37L1 KTN1 LRP10 MFSD6 PDCD1 RUSF1 SLC35C2 SLC38A1 SLC38A7 SLC41A2 SLC7A1 SMIM3 TAS2R10 TMEM147 TMEM218 TMEM239 TMEM97
Entrez ID		64755	80380
HPRD ID		07839	16147
Ensembl ID		ENSG00000140688	ENSG00000197646
Uniprot IDs		A0A024QZE6 Q96GQ5	Q9BQ51
PDB IDs			6UMT
Enriched GO Terms of Interacting Partners?
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