SGCD and SERPINA3

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		SGCD	SERPINA3
Description		sarcoglycan delta	serpin family A member 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Sarcoglycan Complex Integral Component Of Membrane Sarcolemma	Extracellular Region Extracellular Space Nucleus Platelet Alpha Granule Lumen Secretory Granule Lumen Azurophil Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function		DNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding
	Biological Process	Muscle Organ Development Cardiac Muscle Tissue Development Heart Contraction	Acute-phase Response Inflammatory Response Negative Regulation Of Endopeptidase Activity Regulation Of Lipid Metabolic Process Maintenance Of Gastrointestinal Epithelium
Pathways			Platelet degranulation Neutrophil degranulation
Drugs			Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Age at first birth ( 34211149) Airway responsiveness in chronic obstructive pulmonary disease ( 25514360) Anthropometric traits ( 19260139) Daytime sleep phenotypes ( 27126917) Egg allergy ( 25710614) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Evening vs. morning chronotype (sMEQ score) ( 32579418) Glycemic traits (pleiotropy) ( 31021400) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HIV-1 viral setpoint ( 26039976) Mental health related quality of life ( 33578652) Multiple sclerosis (age of onset) ( 19010793) Obesity-related traits ( 23251661) Pulse pressure ( 30578418) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Resting-state electroencephalogram vigilance ( 29703947) Schizophrenia ( 33169155) Smoking initiation ( 33082346) Superior temporal sulcus banks volume ( 31530798) T-Cell Immunoglobulin and Mucin domain 1 levels ( 32460577)	Blood protein levels ( 30072576 28240269) Body mass index ( 23669352) Prostate-specific antigen levels ( 28139693) Serum total protein level ( 29403010)
Interacting Genes		6 interacting genes: ADA FLNC SERPINA3 SGCA SGCB SGCG	28 interacting genes: ABCC5 ADAMTS4 ADH1B APP CELA1 CMA1 CTRB1 CTRC CTRL CTSG DNAJC1 ELANE ERBB2 F5 HOXB1 HSP90AA1 KLK13 KLK2 KLK3 KLK4 LAMC3 LMNB1 MMP1 MST1 NFKB1 POLA1 POLR1H SGCD
Entrez ID		6444	12
HPRD ID		03246	00120
Ensembl ID		ENSG00000170624	ENSG00000196136
Uniprot IDs		Q92629	A0A024R6P0 P01011
PDB IDs			1AS4 1QMN 2ACH 3CAA 3DLW 4CAA 6HGE
Enriched GO Terms of Interacting Partners?
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