PALS1 and DLGAP4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PALS1	DLGAP4
Description		protein associated with LIN7 1, MAGUK p55 family member	DLG associated protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Plasma Membrane Adherens Junction Bicellular Tight Junction Apical Plasma Membrane Axon Protein-containing Complex Myelin Sheath Adaxonal Region Perikaryon Lateral Loop Schmidt-Lanterman Incisure Extracellular Exosome	Plasma Membrane Neuromuscular Junction Glutamatergic Synapse Cholinergic Synapse Postsynaptic Specialization
	Molecular Function	Protein Binding ATP Binding Protein Domain Specific Binding	Protein Binding Molecular Adaptor Activity
	Biological Process	Morphogenesis Of An Epithelial Sheet Gene Expression Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Central Nervous System Neuron Development Cerebral Cortex Development Peripheral Nervous System Myelin Maintenance Myelin Assembly Protein Localization To Myelin Sheath Abaxonal Region Protein Localization To Plasma Membrane	Signaling Regulation Of Postsynaptic Neurotransmitter Receptor Activity
Pathways		Tight junction interactions	Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS			Low density lipoprotein cholesterol levels ( 32154731) Neuroblastoma or malignant cutaneous melanoma ( 31605138)
Interacting Genes		17 interacting genes: ARF6 BHLHB9 CRB3 DLGAP4 FTCD LIN7A LIN7B LIN7C MPP4 NEK9 NUMB PARD6B PATJ SNTG2 SOCS4 SRGAP2B TRAF2	33 interacting genes: ABI2 ALDH16A1 ATPAF2 BIN1 DLG1 DLG3 DLG4 EXOC4 FHL3 FHL5 FKBP6 FYN GRIN1 GRIN2D MAGEA6 MPP7 MTUS2 NCK1 NCK2 NKX2-2 PALS1 PLP2 PPP1R1B SH3GL2 SH3RF1 SHANK2 SHANK3 SLC9A3R1 SLC9A3R2 SORBS2 SYNGAP1 UBASH3A UBC
Entrez ID		64398	22839
HPRD ID		09508	16826
Ensembl ID		ENSG00000072415	ENSG00000080845
Uniprot IDs		Q658X5 Q8N3R9	A0A0B4J2C2 Q9Y2H0
PDB IDs		1Y76 3UIT 4UU5 4UU6 4WSI
Enriched GO Terms of Interacting Partners?
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