SRSF6 and RBM10

Number of citations of the paper that reports this interaction (PubMedID 22365833)
163

Data Source:
BioGRID (two hybrid, two hybrid)

		SRSF6	RBM10
Description		serine and arginine rich splicing factor 6	RNA binding motif protein 10
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nuclear Speck	Nucleus Nuclear Speck Protein-containing Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding	RNA Binding Protein Binding MiRNA Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Splice Site Selection Regulation Of Keratinocyte Proliferation Response To Insulin Negative Regulation Of Keratinocyte Differentiation Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Negative Regulation Of Cell Death Regulation Of Wound Healing Negative Regulation Of Type B Pancreatic Cell Apoptotic Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Biological_process Negative Regulation Of Cell Population Proliferation Positive Regulation Of Smooth Muscle Cell Apoptotic Process Negative Regulation Of MRNA Splicing, Via Spliceosome 3'-UTR-mediated MRNA Stabilization
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Adult body size ( 32376654) Antibody level in response to infection ( 25758998) Daytime sleep phenotypes ( 27126917) HDL cholesterol levels in HIV infection ( 33109212)
Interacting Genes		16 interacting genes: APP CLK1 LUC7L LUC7L2 OGT PPARGC1A RBM10 RNPS1 SF3B4 SREK1 SRPK1 SRPK2 SRSF4 TERF1 TERF2 TOE1	70 interacting genes: AKAP9 ATE1 ATN1 BAHD1 BEND7 CASK CBLL1 CCAR1 CEP70 CPSF7 CSNK2A1 DDX17 DDX5 FAM124A GTSE1 HNRNPH2 HNRNPK HNRNPLL IK KHDRBS2 KLF1 MAPRE2 MBD6 MDM2 MEOX2 MIR106B MIR107 MIR128-1 MIR21 MIR214 MIRLET7A1 MIRLET7A3 MIRLET7D MIRLET7E MIRLET7G MIRLET7I NDEL1 NIN PATZ1 PCBP1 PRC1 PRCC PRDM14 PRR20A PTBP1 PTBP2 RBM12B RBM14 RBM4 RBMY1F SF1 SF3A1 SF3B2 SF3B4 SLAIN1 SNU13 SREK1 SRSF6 TBC1D22B THAP1 TLE5 U2AF1 UBQLN4 ZBTB24 ZFP64 ZNF275 ZNF317 ZNF408 ZNF473 ZNF526
Entrez ID		6431	8241
HPRD ID		09054	02095
Ensembl ID		ENSG00000124193	ENSG00000182872
Uniprot IDs		Q13247	A0A0S2Z4W4 A0A0S2Z4X1 P98175 Q7Z3D7
PDB IDs			2LXI 2M2B 2MXV 2MXW 5ZSW 5ZSY
Enriched GO Terms of Interacting Partners?
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