SRSF3 and SREK1

Number of citations of the paper that reports this interaction (PubMedID 10757789)
19

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		SRSF3	SREK1
Description		serine and arginine rich splicing factor 3	splicing regulatory glutamic acid and lysine rich protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Nuclear Speck	Nucleoplasm Spliceosomal Complex Nuclear Speck
	Molecular Function	RNA Binding Protein Binding Phospholipase Binding Sequence-specific MRNA Binding	RNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Export From Nucleus Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Leukemia Inhibitory Factor	MRNA Processing RNA Splicing
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Glaucoma (primary open-angle) ( 33627673) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Logical memory (delayed recall) in mild cognitive impairment ( 29274321) Systolic blood pressure ( 30224653)
Interacting Genes		40 interacting genes: - APP CHD1 CIRBP CLK1 CLK2 CLK3 CNNM3 DUX4 EXOSC6 GEMIN2 HMGB1 HNRNPK IL7R LNX1 NXF1 PCBP1 PCBP2 PCBP3 PCDHB14 PRPF31 RBM3 RBM7 RBMX RBMY1A1 RNPS1 RPL9 SCAF11 SDCBP SREK1 SRPK1 SRPK2 SRSF2 SRSF8 TRA2B U2AF1 U2AF2 YWHAB YWHAG YWHAQ	60 interacting genes: ARL6IP4 CD8A CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 GPRASP2 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 NCL NPM1 PABPC1 PABPC4 PARP1 PIN1 PRPF40A RACK1 RBM10 RBM39 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B TXLNA YBX1 ZRANB2
Entrez ID		6428	140890
HPRD ID		04530	18043
Ensembl ID		ENSG00000112081	ENSG00000153914
Uniprot IDs		B2R6F3 P84103	Q8WXA9
PDB IDs		2I2Y 2I38
Enriched GO Terms of Interacting Partners?
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