MMS19 and GTF2H1

Number of citations of the paper that reports this interaction (PubMedID 11071939)
7

Data Source:
HPRD (in vitro, in vivo)

		MMS19	GTF2H1
Description		MMS19 homolog, cytosolic iron-sulfur assembly component	general transcription factor IIH subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIIH Holo Complex Cytoplasm Microtubule Organizing Center Spindle Cytosol Membrane MMXD Complex CIA Complex	Transcription Factor TFIIH Core Complex Nucleoplasm Transcription Factor TFIIH Holo Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding Enzyme Binding Signaling Receptor Complex Adaptor Activity Estrogen Receptor Binding Protein-macromolecule Adaptor Activity	Chromatin Binding Protein Binding Thyroid Hormone Receptor Binding
	Biological Process	Phosphorelay Signal Transduction System DNA Metabolic Process DNA Repair Nucleotide-excision Repair Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Chromosome Segregation Response To Hormone Iron-sulfur Cluster Assembly Positive Regulation Of Transcription, DNA-templated Protein Maturation By Iron-sulfur Cluster Transfer Positive Regulation Of Double-strand Break Repair Via Homologous Recombination	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity DNA Repair Nucleotide-excision Repair Transcription By RNA Polymerase I Transcription By RNA Polymerase II Hormone-mediated Signaling Pathway Positive Regulation Of Transcription, DNA-templated Phosphorylation Of RNA Polymerase II C-terminal Domain
Pathways		Cytosolic iron-sulfur cluster assembly	Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex RNA Pol II CTD phosphorylation and interaction with CE during HIV infection HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome Formation of HIV-1 elongation complex containing HIV-1 Tat Tat-mediated elongation of the HIV-1 transcript NoRC negatively regulates rRNA expression Formation of Incision Complex in GG-NER Dual Incision in GG-NER RNA Polymerase II Pre-transcription Events Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER TP53 Regulates Transcription of DNA Repair Genes mRNA Capping RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase I Transcription Termination RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Elongation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Pol II CTD phosphorylation and interaction with CE
Drugs
Diseases
GWAS		Early spontaneous preterm birth ( 31194736) Spontaneous preterm birth with premature rupture of membranes ( 31194736) Waist circumference adjusted for body mass index ( 34021172)	Amyloid A serum levels ( 21124955) Blood protein levels ( 28240269) Pancreatic cancer ( 23180869) Serum metabolite levels ( 33031748 23093944) Survival in pancreatic cancer ( 28470677) Systemic lupus erythematosus ( 33272962)
Interacting Genes		9 interacting genes: ESR1 ESR2 GTF2H1 MAGEF1 MTNR1A NCOA3 RARA SUMO2 THRB	46 interacting genes: ACTN1 AGTRAP AR ATF7IP BRPF1 CCNH CCSER2 CDK7 E2F1 EAF1 ERCC2 ERCC3 ERCC4 ERCC5 ESR1 FHL2 FUBP1 GTF2E1 GTF2E2 GTF2H2 HNF4A HNRNPU HOXC11 JDP2 KIF13A KPNA3 MCM2 MMS19 MNAT1 OGT PIK3R1 PLCG1 POU2AF1 PSMC2 RAD23A REEP5 RXRB TNIP1 TP53 TRIOBP TXNRD2 UBC USHBP1 XPA XPC ZSCAN1
Entrez ID		64210	2965
HPRD ID		17579	01807
Ensembl ID		ENSG00000155229	ENSG00000110768
Uniprot IDs		Q96T76	A0A384MTQ8 P32780
PDB IDs			1PFJ 2DII 2RNR 2RUK 2RVB 5GOW 5XV8 6NMI 6O9L 6O9M 7BUL
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?