SELPLG and SELP

Number of citations of the paper that reports this interaction (PubMedID 9128259)
38

Data Source:
HPRD (in vitro, in vivo)

		SELPLG	SELP
Description		selectin P ligand	selectin P
Image
GO Annotations	Cellular Component	Uropod Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Plasma Membrane Raft	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Platelet Dense Granule Membrane Platelet Alpha Granule Membrane
	Molecular Function	Virus Receptor Activity Signaling Receptor Binding Protein Binding	Lipopolysaccharide Binding Calcium Ion Binding Protein Binding Heparin Binding Sialic Acid Binding Fucose Binding Glycosphingolipid Binding Calcium-dependent Protein Binding Oligosaccharide Binding
	Biological Process	Cell Adhesion Hemopoiesis Viral Entry Into Host Cell Leukocyte Migration Leukocyte Tethering Or Rolling Leukocyte Adhesive Activation Cellular Response To Interleukin-6	Positive Regulation Of Leukocyte Migration Inflammatory Response Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Positive Regulation Of Platelet Activation Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Response To Lipopolysaccharide Regulation Of Integrin Activation Response To Cytokine Calcium-mediated Signaling Using Intracellular Calcium Source Defense Response To Gram-negative Bacterium Leukocyte Tethering Or Rolling Positive Regulation Of Leukocyte Tethering Or Rolling
Pathways		Cell surface interactions at the vascular wall	Platelet degranulation Cell surface interactions at the vascular wall
Drugs			Heparin N-acetyl-alpha-neuraminic acid Dalteparin Nadroparin Crizanlizumab
Diseases
GWAS		Acne (severe) ( 24927181) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Conduct disorder (symptom count) ( 20585324)	Activated partial thromboplastin time ( 22703881) Blood protein levels ( 30072576 29875488 28240269) Hippocampal atrophy ( 22745009) Inflammatory bowel disease ( 26192919) L-selectin levels ( 25576479) Late-onset Alzheimer's disease ( 27770636) Monocyte count ( 32888494) Optic disc size ( 31809533) Soluble levels of adhesion molecules ( 20167578) Total ventricular volume ( 21116278)
Interacting Genes		17 interacting genes: BACE1 CIT CTSG ECSIT GALNT4 MAGEA1 MSN MVK SELE SELL SELP SLC13A1 SYK TNIP1 TPST1 TPST2 VCAN	11 interacting genes: AP1M1 CD24 EZR FCER1G FUT4 GP1BA SELPLG SERPING1 SNX17 SNX27 VCAN
Entrez ID		6404	6403
HPRD ID		02845	01433
Ensembl ID		ENSG00000110876	ENSG00000174175
Uniprot IDs		Q14242	A0A024R8Y9 P16109 Q5R341 Q6NUL9
PDB IDs		1G1S	1FSB 1G1Q 1G1R 1G1S 1HES 1KJD
Enriched GO Terms of Interacting Partners?
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