SEC13 and HAPLN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SEC13	HAPLN2
Description		SEC13 homolog, nuclear pore and COPII coat complex component	hyaluronan and proteoglycan link protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Nuclear Envelope Nucleoplasm Lysosomal Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat Nuclear Pore Outer Ring Intracellular Membrane-bounded Organelle GATOR2 Complex Extracellular Exosome	Extracellular Region Extracellular Matrix
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding	Protein Binding Hyaluronic Acid Binding
	Biological Process	Protein Import Into Nucleus Intracellular Protein Transport Positive Regulation Of TOR Signaling Protein Exit From Endoplasmic Reticulum MRNA Transport COPII-coated Vesicle Cargo Loading COPII-coated Vesicle Budding Positive Regulation Of TORC1 Signaling	Skeletal System Development Cell Adhesion Central Nervous System Development Establishment Of Blood-nerve Barrier Extracellular Matrix Assembly
Pathways		ISG15 antiviral mechanism Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly COPII-mediated vesicle transport MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) RHO GTPases Activate Formins tRNA processing in the nucleus Mitotic Prometaphase HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation Amino acids regulate mTORC1 EML4 and NUDC in mitotic spindle formation Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		14 interacting genes: ADGRF5 CFAP43 CLDN12 EGFR HAPLN2 HSPB1 LTB4R2 NUP98 OXNAD1 RAB11A SEC16B SEC31A TRAF5 WDR44	47 interacting genes: ASB13 BANP CCDC125 CIDEB EXOSC8 FHL3 FHL5 FNDC3B GOLGA6L9 GPRIN2 KRT15 KRT27 KRT31 KRT33B KRT34 KRT35 KRT37 KRT40 KRT85 KRTAP10-8 KRTAP19-5 KRTAP2-3 KRTAP2-4 KRTAP6-2 KRTAP6-3 KRTAP9-2 MDFI MID2 MTUS2 NBPF19 NOTCH2NLA OIP5 PFDN5 PM20D2 PNMA1 PNMA2 PPP1R16B PSTPIP1 SEC13 SSC4D TFCP2 TRIM23 TRIM27 VWC2 ZMYND12 ZNF438 ZNF655
Entrez ID		6396	60484
HPRD ID		02538	17088
Ensembl ID		ENSG00000157020	ENSG00000132702
Uniprot IDs		A8MWR8 P55735	Q9GZV7
PDB IDs		3BG0 3BG1 5A9Q
Enriched GO Terms of Interacting Partners?
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