SAT1 and GBP2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SAT1	GBP2
Description		spermidine/spermine N1-acetyltransferase 1	guanylate binding protein 2
Image
GO Annotations	Cellular Component	Cytosol	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Diamine N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity Spermidine Binding Identical Protein Binding	GTPase Activity Protein Binding GTP Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Angiogenesis Polyamine Biosynthetic Process Putrescine Catabolic Process Spermidine Acetylation	Immune Response Protein Localization To Nucleus Defense Response To Protozoan Defense Response To Gram-positive Bacterium Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor
Pathways		Interconversion of polyamines	Interferon gamma signaling Interferon alpha/beta signaling
Drugs		N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Diseases
GWAS		Shoulder impingement or rotator cuff tear ( 33482370)	Serum metabolite levels ( 33031748)
Interacting Genes		98 interacting genes: ABCB8 ABHD15 APLP1 B4GALT3 BHLHA9 C19orf25 CASP7 CCDC148 CCDC90B CCHCR1 CDC42EP1 CEP126 CHD3 COPS6 COX6C CRMP1 CSNK2A1 CSNK2A2 DDX39A DGKZ DIPK1B DMRT3 DNPEP EEF1G EIF3D EPHB6 ERG28 EVA1A FAM156A FAM228A FAM86C1P FH FTSJ3 FUNDC2 GAS2L2 GBP2 GDF9 HIF1A HOXB6 HOXB9 HSPB1 HSPE1 INO80C ITGA9 JUNB KAT5 KAT7 KCNA4 KHDC4 LHX3 LNX1 LRIF1 LUC7L2 LYRM7 MED31 MEOX2 MRPL12 MRPL9 MTA1 MYPOP NIF3L1 NMRK2 NTAQ1 PLGRKT PRDX2 PSMA1 PTN RACK1 RBM17 RBM48 REL RELA RPLP1 RPP25 SARAF SAT2 SEPHS1 SETDB1 SNAI2 TACO1 TCF25 TEAD4 TEX43 TLE1 TLE5 TNNI1 TP53 TP53TG1 TSC22D4 TUBB2A TXN2 UBE2D3 UNC119 USHBP1 UTP14A VASP VKORC1 ZHX1	23 interacting genes: ANXA7 BID BNIP3L BTBD2 CSNK2B FBXO7 FXR1 GADD45A GSK3B HSPE1 KLHL20 LRRC8B LSM2 MAGI1 MAPK8IP2 PAFAH1B3 PPP1R8 RPS6KA1 SAT1 SEPHS1 SERPINB9 STK3 TFG
Entrez ID		6303	2634
HPRD ID		02431	02682
Ensembl ID		ENSG00000130066	ENSG00000162645
Uniprot IDs		A0A384NQ10 P21673	P32456 Q8TCE5
PDB IDs		2B3U 2B3V 2B4B 2B4D 2B58 2B5G 2F5I 2FXF 2G3T 2JEV	6VKJ
Enriched GO Terms of Interacting Partners?
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