RXRB and NR4A2

  • Number of citations of the paper that reports this interaction (PubMedID 7758108)
  • 170
  • Data Source:
  • BioGRID (two hybrid)
  • HPRD (in vitro, two hybrid, in vivo)

RXRB

NR4A2

Description retinoid X receptor beta nuclear receptor subfamily 4 group A member 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Age at voice drop ( 27182965)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Anxiety ( 33859377)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Depression ( 29700475)
  • HDL cholesterol levels ( 32109663)
  • Leisure-time exercise behaviour ( 30102679)
  • Leisure-time exercise behaviour (age-stratified) ( 30102679)
  • Lung function (FEV1/FVC) ( 30061609)
  • Menarche (age at onset) ( 21102462 25231870)
  • Response to statin therapy ( 20339536)
  • Schizophrenia ( 33169155)
  • Sociability score ( 34054130)
  • Worry too long after an embarrassing experience ( 34054130)
Interacting Genes 49 interacting genes: AKAP13 CACNA1B CALCOCO2 CCDC57 EXOSC8 GOLGA2 GTF2H1 KRT40 MAP4 MID2 MYG1 NCOA1 NCOA3 NR0B2 NR1H2 NR1H3 NR1H4 NR1I2 NR2C2 NR2E3 NR3C1 NR4A2 NRIP1 PICK1 PLSCR1 PPARD PPARG PSTPIP1 PTMS RARA RARB RARG SIAH1 SLIT3 SPOP SPOPL TACC2 TADA3 TAF11 TFCP2 TFIP11 THRA THRB TP53BP2 TRIM27 TRIM37 UBL7 VDR ZDHHC12 18 interacting genes: BAZ1B CDKN1C CDKN2D CHST13 COPS5 FAP MAPK1 ODAD2 PIAS4 PPARG RPS6KA1 RXRA RXRB SMARCA2 SMARCA4 SMPD4 TCEAL5 VHL
Entrez ID 6257 4929
HPRD ID 01578 03493
Ensembl ID ENSG00000204231 ENSG00000153234
Uniprot IDs A0A0G2JKR7 A0A0S2Z570 B7Z7J5 P28702 Q5STP9 F1D8N6 F1DAL2 P43354 Q53EL4
PDB IDs 1H9U 1UHL 5HJP 5I4V 5KYA 5KYJ 7A78 1OVL 5Y41 5YD6 6DDA 6L6L 6L6Q
Enriched GO Terms of Interacting Partners?
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