RSU1 and LIMS1

Number of citations of the paper that reports this interaction (PubMedID 15878342)
45

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		RSU1	LIMS1
Description		Ras suppressor protein 1	LIM zinc finger domain containing 1
Image
GO Annotations	Cellular Component	Cytosol Focal Adhesion Extracellular Exosome	Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Protein Kinase Binding Protein-containing Complex Binding
	Biological Process	Signal Transduction Regulation Of Cell-substrate Adhesion Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of GTPase Activity	Epithelial To Mesenchymal Transition Cell Aging Positive Regulation Of Gene Expression Positive Regulation Of Cell-substrate Adhesion Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of GTPase Activity Establishment Of Protein Localization Cell-cell Junction Organization Negative Regulation Of Transcription, DNA-templated Regulation Of Epithelial Cell Proliferation Positive Regulation Of Focal Adhesion Assembly Cellular Response To Transforming Growth Factor Beta Stimulus Cell-cell Adhesion Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways		Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	Cell-extracellular matrix interactions Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Drugs
Diseases
GWAS		Adult body size ( 32376654) Bone mineral content ( 31790847) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Initial alcohol sensitivity ( 30276832) Major depressive disorder ( 29317602) Metabolite levels ( 23823483) Nicotine dependence symptom count ( 25555482) Obesity-related traits ( 23251661) Platelet count ( 32888494) Platelet distribution width ( 32888494) Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave. ( 28394258) Urinary albumin excretion ( 21355061) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)	Apolipoprotein B levels ( 32203549) Beard thickness ( 26926045) Birth weight ( 31043758) Excessive hairiness ( 29895819) Eyebrow thickness ( 26926045) Immature fraction of reticulocytes ( 32888494) LDL cholesterol ( 30275531) LDL cholesterol levels ( 32203549) Monobrow thickness ( 26926045) Scalp hair shape ( 26926045) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		5 interacting genes: APP GSK3B HGS LIMS1 RAF1	48 interacting genes: ADAMTS9 ATXN10 CATSPER1 CCN2 COL8A1 CSRP3 CWF19L2 DAPK1 EHMT2 FAM90A1 FERMT2 FERMT3 FMR1 GEM ILK INO80B IPO7 KAT8 KPRP LMO3 LPXN MBIP MYO15B NCK2 NEB OSR2 PARVA PEG3 PLCE1 RAD51D RBBP8 RSU1 SCNM1 SMURF1 TBC1D22B TCEA2 TGFBR1 TMSB4X TRIO TTN USP11 ZIM2 ZMYM4 ZNF160 ZNF410 ZNF417 ZNF564 ZNF587
Entrez ID		6251	3987
HPRD ID		01551	03978
Ensembl ID		ENSG00000148484	ENSG00000169756
Uniprot IDs		Q15404	P48059
PDB IDs		7D2S 7D2T 7D2U	1G47 1NYP 1U5S 2COR 2D8X 2KBX 3F6Q 4HI8 4HI9 6MIF 7D2S 7D2T 7D2U
Enriched GO Terms of Interacting Partners?
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