RPS2 and USP47

Number of citations of the paper that reports this interaction (PubMedID 32370049)
2

Data Source:
BioGRID (pull down, affinity chromatography technology)

		RPS2	USP47
Description		ribosomal protein S2	ubiquitin specific peptidase 47
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytosol Focal Adhesion Membrane Cytosolic Ribosome Cytosolic Small Ribosomal Subunit Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol SCF Ubiquitin Ligase Complex
	Molecular Function	RNA Binding MRNA Binding Structural Constituent Of Ribosome Protein Binding Fibroblast Growth Factor Binding Enzyme Binding Cadherin Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase Protein Binding WD40-repeat Domain Binding Deubiquitinase Activity
	Biological Process	Cytoplasmic Translation Translation Positive Regulation Of Ubiquitin-protein Transferase Activity	Base-excision Repair Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Response To Xenobiotic Stimulus Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Deubiquitination Positive Regulation Of Cell Growth Regulation Of Protein Stability Cellular Response To UV Monoubiquitinated Protein Deubiquitination Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis RMTs methylate histone arginines rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Protein methylation Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Ub-specific processing proteases
Drugs		Copper
Diseases
GWAS		Atrial fibrillation ( 29892015) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)	Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		22 interacting genes: ANXA2 ANXA7 CDKN1A DNM2 DUX4 FBXO7 FGF1 FGF3 GABARAPL2 GADD45A GRB7 GSK3B MPP3 OGT PTEN PTK7 SMN1 SOX5 TK1 TRAF6 USP47 YWHAG	7 interacting genes: AP4M1 MED29 MED9 PLA2G2A RPS2 SNCA UBC
Entrez ID		6187	55031
HPRD ID		04690	11668
Ensembl ID		ENSG00000140988	ENSG00000170242
Uniprot IDs		P15880	Q68D97 Q96K76
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6G18 6G4S 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBD 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZVH 6ZVJ 6ZXD 6ZXE 6ZXF 6ZXG 6ZXH 7A09 7K5I
Enriched GO Terms of Interacting Partners?
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