RP2 and ARL3

Number of citations of the paper that reports this interaction (PubMedID 11847227)
37

Data Source:
BioGRID (pull down, pull down)
HPRD (in vivo, in vitro)

		RP2	ARL3
Description		RP2 activator of ARL3 GTPase	ADP ribosylation factor like GTPase 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Centriole Plasma Membrane Cilium Nuclear Body Cytoplasmic Vesicle Ciliary Basal Body Extracellular Exosome Periciliary Membrane Compartment	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Spindle Microtubule Cytoplasmic Microtubule Cilium Microtubule Cytoskeleton Midbody Photoreceptor Connecting Cilium Extracellular Exosome
	Molecular Function	Magnesium Ion Binding GTPase Activator Activity Protein Binding GTP Binding Unfolded Protein Binding	Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding GDP Binding GTPase Activating Protein Binding
	Biological Process	Cell Morphogenesis Protein Folding Post-Golgi Vesicle-mediated Transport Post-chaperonin Tubulin Folding Pathway Visual Perception Protein Transport Regulation Of Catalytic Activity Cilium Assembly	Mitotic Cytokinesis Kidney Development Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Smoothened Signaling Pathway Small GTPase Mediated Signal Transduction Protein Transport Positive Regulation Of Microtubule Polymerization Intraciliary Transport Photoreceptor Cell Development Cilium Assembly Protein Localization To Cilium Protein Localization To Ciliary Membrane
Pathways		Trafficking of myristoylated proteins to the cilium	Trafficking of myristoylated proteins to the cilium
Drugs			2-(N-morpholino)ethanesulfonic acid Guanosine-5'-Diphosphate
Diseases
GWAS			Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure ( 30487518) Hip circumference adjusted for BMI ( 34021172) Mean arterial pressure ( 30487518) Mean arterial pressure (long-term average) ( 28348047) Prostate cancer ( 23535732) Pulse pressure ( 30487518) Refractive error ( 32231278) Schizophrenia ( 28991256 25056061 27922604) Systolic blood pressure ( 30487518) Systolic blood pressure (long-term average) ( 28348047) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		3 interacting genes: ARL3 OSTF1 PM20D2	12 interacting genes: ARL2BP GOLGA4 LRIF1 PDE6D PTEN RP2 TBL1X TLE1 TP53 TUBA1A UBR1 UNC119
Entrez ID		6102	403
HPRD ID		02424	05260
Ensembl ID		ENSG00000102218	ENSG00000138175
Uniprot IDs		A0A1B2JLU2 O75695	P36405
PDB IDs		2BX6 3BH6 3BH7
Enriched GO Terms of Interacting Partners?
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