ROS1 and FGFR4

  • Number of citations of the paper that reports this interaction (PubMedID 28205554)
  • 52
  • Data Source:
  • BioGRID (fluorescent resonance energy transfer)

ROS1

FGFR4

Description ROS proto-oncogene 1, receptor tyrosine kinase fibroblast growth factor receptor 4
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder ( 31043756)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Facial emotion recognition (fearful faces) ( 28608620)
  • Lung adenocarcinoma ( 28604730)
  • Lung cancer ( 23143601)
  • Night sleep phenotypes ( 27126917)
  • Pneumococcal meningitis ( 31092817)
  • QT interval (drug interaction) ( 23459443)
  • Activated partial thromboplastin time ( 22703881)
  • Apolipoprotein A1 levels ( 32203549)
  • Body fat distribution (arm fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Body shape index ( 34021172)
  • Circulating fibroblast growth factor 23 levels ( 30217807)
  • Height ( 28552196 25282103 31562340)
  • Hemoglobin levels ( 32327693)
  • Hip circumference adjusted for BMI ( 34021172)
  • Hip index ( 34021172)
  • Hip shape (DXA scan) ( 30320955)
  • Narrowest width of the femoral neck ( 30888730)
  • Nonsyndromic cleft lip ( 31609978)
  • Type 2 diabetes ( 32499647 30718926)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for BMI in smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 34021172 25673412 28448500)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172 26426971)
  • Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
  • Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
  • Waist-to-hip ratio adjusted for body mass index ( 26785701 25673412)
Interacting Genes 7 interacting genes: ABL1 ADGRL1 FGFR4 IKBKG PTPN11 PTPN6 VAV3 85 interacting genes: ABCB5 AKT1 ANGPTL4 ARAF ARNT BECN1 BLID CASC3 CBLC CCND2 CCNE1 CD44 CDH2 CDK4 CDK6 CDKN2A CDKN2B CDKN2C DIRAS3 EPHA2 EPHA4 EPSTI1 ERBB2 ERRFI1 FGF1 FGF17 FGF18 FGF19 FGF2 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FZR1 GLCE GLIS2 GRM1 HGF HIF1A IFT80 IGF1R KDELR2 LATS2 LRATD2 MAP2K5 MAP2K6 MAP3K5 MAPK14 MDM4 MET MSH2 MTA3 MYC NF2 NSD3 OSGIN1 PDGFRA PDLIM2 PLCG1 PPP3CA PSMC3IP PTPN11 PTPN12 PTPN6 PTPRR RAF1 RASL10B RASSF1 RNF20 ROS1 SCGB3A1 STAT1 STAT3 STC2 STK11 TEAD2 TERT THRSP TP53 TSC1 TTYH2 WIF1
Entrez ID 6098 2264
HPRD ID 01295 00625
Ensembl ID ENSG00000047936 ENSG00000160867
Uniprot IDs P08922 B4DVP5 J3KPQ0 P22455
PDB IDs 3ZBF 4UXL 1QCT 4QQ5 4QQC 4QQJ 4QQT 4QRC 4R6V 4TYE 4TYG 4TYI 4TYJ 4UXQ 4XCU 5JKG 5NUD 5NWZ 5XFF 5XFJ 6IUO 6IUP 6J6Y 6JPE 6JPJ 6NVG 6NVH 6NVI 6NVJ 6NVK 6V9C 6YI8
Enriched GO Terms of Interacting Partners?
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