RHO and SAG

Number of citations of the paper that reports this interaction (PubMedID 1917988)
41

Data Source:
HPRD (in vitro, in vivo)

		RHO	SAG
Description		rhodopsin	S-antigen visual arrestin
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Photoreceptor Outer Segment Photoreceptor Inner Segment Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Integral Component Of Membrane Golgi-associated Vesicle Membrane Photoreceptor Outer Segment Membrane Ciliary Membrane Photoreceptor Inner Segment Membrane Sperm Midpiece Photoreceptor Disc Membrane Sperm Head Plasma Membrane	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytosol Membrane
	Molecular Function	G Protein-coupled Receptor Activity 11-cis Retinal Binding Protein Binding G Protein-coupled Photoreceptor Activity Metal Ion Binding	G Protein-coupled Receptor Binding Opsin Binding Protein Phosphatase Inhibitor Activity Protein Binding Phosphoprotein Binding
	Biological Process	Protein Phosphorylation G Protein-coupled Receptor Signaling Pathway Visual Perception Phototransduction Phototransduction, Visible Light Absorption Of Visible Light Rhodopsin Mediated Signaling Pathway Protein-chromophore Linkage Thermotaxis Photoreceptor Cell Maintenance Detection Of Temperature Stimulus Involved In Thermoception Retina Development In Camera-type Eye Cellular Response To Light Stimulus	G Protein-coupled Receptor Internalization Cell Surface Receptor Signaling Pathway Rhodopsin Mediated Signaling Pathway Negative Regulation Of Catalytic Activity
Pathways		The canonical retinoid cycle in rods (twilight vision) Activation of the phototransduction cascade Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade G alpha (i) signalling events Opsins VxPx cargo-targeting to cilium VxPx cargo-targeting to cilium	Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade
Drugs		Halothane N-Acetylmethionine 1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine B-nonylglucoside Phosphonothreonine B-2-Octylglucoside Hexadecanal Palmitic Acid Heptane-1,2,3-Triol Dodecyldimethylamine N-oxide (Hydroxyethyloxy)Tri(Ethyloxy)Octane Heptyl 1-Thiohexopyranoside Dexfosfoserine
Diseases
GWAS		Diisocyanate-induced asthma ( 25918132) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Calcium levels ( 20705733) Crohn's disease ( 22412388) Estimated glomerular filtration rate ( 31152163)
Interacting Genes		12 interacting genes: ARR3 ARRB2 CD79A DERL1 GNGT1 GRK1 GRK2 GRK5 GRK6 PPP2CA PRKCA SAG	5 interacting genes: ADRA1B CHRM2 CLK3 EIF4E2 RHO
Entrez ID		6010	6295
HPRD ID		01584	01625
Ensembl ID		ENSG00000163914	ENSG00000130561
Uniprot IDs		P08100	P10523
PDB IDs		4ZWJ 5DGY 5W0P 6CMO
Enriched GO Terms of Interacting Partners?
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