BCL2L2 and APOC2

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

BCL2L2

APOC2

Description BCL2 like 2 apolipoprotein C2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (onset between ages 58 and 79) ( 30979435)
  • Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
  • Blood protein levels ( 28240269)
  • Carotid intima media thickness (maximum) ( 31801372)
  • Carotid intima media thickness (mean) ( 31801372)
  • Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 29274321)
  • Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal AB1-42 levels in normal cognition ( 29274321)
  • Cerebrospinal fluid AB1-42 levels ( 29274321)
  • Cerebrospinal fluid p-tau levels ( 29274321)
  • Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321)
  • Cerebrospinal fluid t-tau levels ( 29274321)
  • Cerebrospinal fluid t-tau levels in mild cognitive impairment ( 29274321)
  • Cholesterol, total ( 20686565)
  • HDL cholesterol ( 20686565)
  • HDL cholesterol levels ( 28334899)
  • Hippocampal volume ( 29274321)
  • Hippocampal volume in Alzheimer's disease dementia ( 29274321)
  • LDL cholesterol ( 18802019 18193044 20864672 19060906 20686565)
  • LDL cholesterol levels ( 28334899)
  • Lipid metabolism phenotypes ( 22286219)
  • Logical memory (delayed recall) ( 29274321)
  • Logical memory (immediate recall) ( 29274321)
  • Low density lipoprotein cholesterol levels ( 28548082)
  • Quantitative traits ( 19197348)
  • Total cholesterol levels ( 28334899 28548082)
  • Triglyceride levels ( 28334899)
  • Triglycerides ( 20686565)
  • Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes 53 interacting genes: ANKS6 APOC1 APOC2 APOC4 ATP5PF BAD BAK1 BAX BBC3 BCL2L11 BHLHA9 BID BIK BMF BNIP3 BNIP5 C10orf67 CD79A CHODL CIDEB CISD2 CLDN7 ERVFRD-1 FATE1 G0S2 GORAB GPR151 GPX8 HRK KASH5 KCNJ6 LMNA LRRIQ1 MGST2 MUC1 PANX1 PPP1CA PSCA RHBDD2 S100B SAR1A SGPL1 SLC35C2 SLC35E3 SLC39A2 SLC39A6 STOM SUSD3 TCF4 TEX11 TMEM139 TMX1 TP53 28 interacting genes: APOE APOL2 BBS2 BCL2L2 CRYAB DIABLO GAD2 GSDMA IFI27 LETMD1 LPL MAIP1 MICOS10 MICOS13 NFU1 PORCN RSAD2 SENP2 SNAP47 SYT16 TBC1D20 THBD TIMMDC1 TMEM14B TPRG1 TTPA UBQLN1 UBQLN2
Entrez ID 599 344
HPRD ID 03569 07457
Ensembl ID ENSG00000129473 ENSG00000234906
Uniprot IDs Q92843 A0A024R0T9 P02655
PDB IDs 1MK3 1O0L 1ZY3 2Y6W 4CIM 1BY6 1I5J 1O8T 1SOH
Enriched GO Terms of Interacting Partners?
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