RET and SHC3

  • Number of citations of the paper that reports this interaction (PubMedID 12242309)
  • 23
  • Data Source:
  • HPRD (in vivo)

RET

SHC3

Description ret proto-oncogene SHC adaptor protein 3
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Logical memory (delayed recall) in Alzheimer's disease dementia ( 29274321)
  • Monocyte count ( 32888494)
  • Pelvic organ prolapse (moderate/severe) ( 26545240)
  • Response to statins (LDL cholesterol change) ( 22331829)
  • Superior parietal cortex volume ( 31530798)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes 44 interacting genes: AKAP5 CBL CBLB CRK DOK1 DOK2 DOK3 DOK4 DOK5 DOK6 DUSP26 ERBB2 FBXO7 FRS2 GAB1 GDNF GFRA1 GRB10 GRB2 GRB7 IKBKG LRRK1 MAPK1 MAPK14 MAPK3 MAPK8 NEDD4 NOTCH2NLA NOTCH3 NRTN PDLIM7 PIK3R1 PLCG1 PRKAR2A PTK2 PTPN11 PTPRA PTPRF PTPRR SHC1 SHC3 SHC4 SRC STAT3 58 interacting genes: ALK ANKRD10 APP AR ARHGAP32 ASPG AXL BMF CCNC CDCA4 CEACAM6 COPS6 CT55 DOK3 EGFR ERBB2 ERBB3 ERBB4 FLT4 FTO GAB1 GOLGA2 GOLGA6L9 GRB2 KIT KRT31 KRT33B KRT34 KRT35 KRT39 KRT40 KRT86 MET NTRK1 NTRK2 PMF1 PNMA1 PPP1R16B PRKAR1B PSMD8 REL RET SH3GL3 SMYD3 STX11 TRAF1 TRAF2 TRIM35 TRIM54 TSC1 UBAP2 USHBP1 USP54 VPS28 WWOX YPEL3 YPEL5 ZMYND12
Entrez ID 5979 53358
HPRD ID 01266 12005
Ensembl ID ENSG00000165731 ENSG00000148082
Uniprot IDs A0A024R7T2 P07949 Q92529
PDB IDs 1XPD 2IVS 2IVT 2IVU 2IVV 2X2K 2X2L 2X2M 2X2U 4CKI 4CKJ 4UX8 5AMN 5FM2 5FM3 6FEK 6GL7 6I82 6I83 6NE7 6NEC 6NJA 6Q2J 6Q2N 6Q2O 6Q2R 6Q2S 6VHG 7JU5 7JU6
Enriched GO Terms of Interacting Partners?
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