SENP2 and ACSF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SENP2	ACSF2
Description		SUMO specific peptidase 2	acyl-CoA synthetase family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Cytosol PML Body Nuclear Membrane	Mitochondrial Matrix
	Molecular Function	Protein Binding SUMO-specific Protease Activity SUMO-specific Endopeptidase Activity	Long-chain Fatty Acid-CoA Ligase Activity Protein Binding ATP Binding Medium-chain Fatty Acid-CoA Ligase Activity Butyrate-CoA Ligase Activity
	Biological Process	Protein Transport Wnt Signaling Pathway Protein Desumoylation Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Protein Destabilization Fat Cell Differentiation MRNA Transport	Long-chain Fatty Acid Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process
Pathways		SUMO is proteolytically processed	Mitochondrial Fatty Acid Beta-Oxidation
Drugs
Diseases
GWAS		Diastolic blood pressure ( 28135244 27841878) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 31152163 31015462) Height ( 28552196) Hip circumference ( 28552196) JT interval ( 29874175) PR interval ( 30046033 32439900) QRS duration ( 30012220) Seborrheic dermatitis ( 29203360) Systolic blood pressure ( 27841878 26969751)	Heel bone mineral density ( 30598549)
Interacting Genes		39 interacting genes: ACSF2 AGTRAP APOC2 APOC4 APP ARL6IP1 ARMC12 AXIN1 CDCA5 CDK5RAP2 DAXX ERCC6 FUNDC1 FZR1 HCCS IKBKG KASH5 KPNA1 KPNB1 LMNA MYC NACC1 NEDD4L NUP153 OGT PML RANGAP1 RETREG3 RPRM SDR16C5 STK38 SUMO1 SUMO2 SUMO3 SYNE4 TMEM239 TNFRSF10D TPD52 TRIM63	18 interacting genes: AGTRAP APOA5 APOC1 ARL13B ARL6IP1 C10orf67 CLEC10A CMTM5 COQ9 CREB3 DGAT2L6 GPR152 MICOS13 RDH10 RHBDD2 SENP2 SIGLEC12 SYNGR3
Entrez ID		59343	80221
HPRD ID		07002	13380
Ensembl ID		ENSG00000163904	ENSG00000167107
Uniprot IDs		Q9HC62	B4DTB9 E9PF16 Q96CM8
PDB IDs		1TGZ 1TH0 2IO0 2IO1 2IO2 2IO3 3ZO5 5AEK
Enriched GO Terms of Interacting Partners?
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