RARA and ARNTL

  • Number of citations of the paper that reports this interaction (PubMedID 11439184)
  • 112

RARA

ARNTL

Description retinoic acid receptor alpha aryl hydrocarbon receptor nuclear translocator like
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Body mass index ( 25673413)
  • C-reactive protein levels ( 30388399)
  • C-reactive protein levels or triglyceride levels (pleiotropy) ( 27286809)
  • Caffeine consumption from tea ( 33287642)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Chronotype ( 30696823)
  • Cooked vegetable consumption ( 32066663)
  • Coronary artery disease ( 32469254 29212778 33020668)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Depression in multiple sclerosis (pre-diagnosis) ( 33296963)
  • Diastolic blood pressure ( 27841878 27618448 30487518)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Face memory ( 31596458)
  • Feeling guilty ( 29500382)
  • Feeling miserable ( 29500382)
  • Fish- and plant-related diet ( 32066663)
  • General risk tolerance (MTAG) ( 30643258)
  • HDL cholesterol ( 30275531)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
  • Iron status biomarkers (transferrin levels) ( 25352340)
  • Lipid traits (pleiotropy) (HIPO component 1) ( 30289880)
  • Mean arterial pressure ( 30487518)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Menarche (age at onset) ( 27182965 21102462 25231870)
  • Metabolic syndrome ( 31589552)
  • Neurociticism ( 29500382)
  • PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia ( 30450575)
  • Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020)
  • Psoriasis ( 30921485)
  • Red blood cell count ( 32888494)
  • Schizophrenia ( 23358160)
  • Sociability score ( 34054130)
  • Systolic blood pressure ( 31928498)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Tea consumption ( 31046077)
  • Triglyceride levels ( 32203549 32154731 31928498 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
  • Worry too long after an embarrassing experience ( 29500382 34054130)
  • Worry/vulnerability (special factor of neuroticism) ( 30867560)
Interacting Genes 98 interacting genes: ACTN4 AKT1 ALOX15B ALX1 ARID1A ARID5A ARNTL BAG1 BBS4 BTG1 CCND3 CCNDBP1 CDK7 CEBPA CLOCK CNOT1 COPS2 E2F1 ESR1 FGFR1 FN1 FOXO1 GADD45G GATA2 HDAC1 HDAC3 HDAC4 HMGA1 HR IRX4 ITGB1BP2 KAT2B KDM5A KLF5 LRIF1 MAPK6 MCRS1 MDM2 MECR MED1 MED25 MED6 MMS19 NCOA1 NCOA2 NCOA3 NCOA6 NCOR1 NCOR2 NKX2-1 NPAS2 NR0B2 NR1H2 NR1H3 NR2C1 NR2E3 NR3C1 NRBF2 NRIP1 NRIP2 NSD1 PARP1 PHF8 PIN1 PLEKHF2 PML PNRC2 POU2F1 PPARG PRAME PRDX6 PRKCA PSMC5 RXRA RXRB RXRG S100A3 SIRT1 SMARCD3 SNW1 SP1 SPEN SRC SRF STAT5B TADA3 TEKT4 THRB TNIP1 TOP2B TRIB3 TRIM24 TRIP4 TUBG1 UBE3A UBQLN1 USP7 ZBTB16 25 interacting genes: AHR AZIN1 BHLHE40 CLOCK CRY1 CSNK1E DELEC1 DHTKD1 EP300 EPAS1 HIF1A HLF HSP90AA1 KAT2B NPAS2 NPAS4 PER3 RARA RHOA RHOU RXRA SIRT1 TRAPPC12 UBE2I ZMYND12
Entrez ID 5914 406
HPRD ID 06769 03973
Ensembl ID ENSG00000131759 ENSG00000133794
Uniprot IDs A8K840 A8MUP8 F1D8N9 P10276 Q6I9R7 A0A140VKD3 A0A669KBF4 B2RCL8 O00327
PDB IDs 1DKF 1DSZ 3A9E 3KMR 3KMZ 4DQM 5K13 6XWG 4H10
Enriched GO Terms of Interacting Partners?
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