RAD51D and VPS9D1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RAD51D	VPS9D1
Description		RAD51 paralog D	VPS9 domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Replication Fork Cytoplasm Centrosome Rad51B-Rad51C-Rad51D-XRCC2 Complex
	Molecular Function	Four-way Junction DNA Binding DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding ATP-dependent Activity, Acting On DNA Gamma-tubulin Binding	Guanyl-nucleotide Exchange Factor Activity Transporter Activity Protein Binding Identical Protein Binding
	Biological Process	Telomere Maintenance Via Recombination Telomere Maintenance Double-strand Break Repair Via Homologous Recombination DNA Repair Reciprocal Meiotic Recombination Interstrand Cross-link Repair Strand Invasion Regulation Of Cell Cycle	ATP Synthesis Coupled Proton Transport Vesicle-mediated Transport Regulation Of Catalytic Activity
Pathways		HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange Presynaptic phase of homologous DNA pairing and strand exchange TP53 Regulates Transcription of DNA Repair Genes Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function
Drugs
Diseases
GWAS			Blood protein levels ( 29875488) Brain morphology (MOSTest) ( 32665545) Mean spheric corpuscular volume ( 32888494) Platelet distribution width ( 32888494)
Interacting Genes		49 interacting genes: AMOTL2 BLM C1orf94 CCDC33 CCNL1 CEP57L1 EFHC2 GEMIN4 HSF2BP IHO1 IKZF1 IKZF3 KATNBL1 KIFC3 KRT15 LIMS1 LNX1 LZTS2 MAPK8IP3 MEOX2 NFKBID PICK1 PNMA1 POLDIP3 PRDM14 PRDM6 RAD51B RAD51C RBM48 REL RHOU RNF138 SORBS3 SPATC1L STX11 SWSAP1 TCF4 TEPSIN TLE5 TRIM14 TTC23 VPS9D1 XRCC2 XRCC3 ZBTB42 ZC2HC1C ZNF343 ZNF774 ZSWIM7	25 interacting genes: AAMDC AHSP AKAP9 CCDC172 CCHCR1 DYDC1 FAM214B HOMEZ KRT31 KRT35 KRT39 MAP1LC3A MKRN3 PNMA1 POU6F2 PSMD2 RAD51D RSPH14 SYT17 TRIM21 TRIM27 TRIM54 TTC23L UBXN11 ZNF655
Entrez ID		5892	9605
HPRD ID		04261	08508
Ensembl ID		ENSG00000185379	ENSG00000075399
Uniprot IDs		O75771	Q9Y2B5
PDB IDs		2KZ3
Enriched GO Terms of Interacting Partners?
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