RAB5C and TBC1D15

Number of citations of the paper that reports this interaction (PubMedID 16923123)
69

Data Source:
BioGRID (two hybrid)

		RAB5C	TBC1D15
Description		RAB5C, member RAS oncogene family	TBC1 domain family member 15
Image			No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Endosome Early Endosome Lipid Droplet Plasma Membrane Endomembrane System Endocytic Vesicle Early Endosome Membrane Azurophil Granule Membrane Melanosome Extracellular Exosome	Extracellular Region Cytoplasm
	Molecular Function	GTPase Activity G Protein Activity Protein Binding GTP Binding GDP Binding	GTPase Activator Activity Protein Binding
	Biological Process	Intracellular Protein Transport Endocytosis Regulation Of Endocytosis Plasma Membrane To Endosome Transport	Intracellular Protein Transport Regulation Of GTPase Activity Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		Golgi Associated Vesicle Biogenesis Neutrophil degranulation TBC/RABGAPs Clathrin-mediated endocytosis RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	TBC/RABGAPs
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Fibrinogen levels ( 28107422 26561523) Mean corpuscular volume ( 32888494) Medication use (thyroid preparations) ( 31015401) Vitiligo ( 27723757) vWF and FVIII levels ( 30586737) White blood cell count ( 32888494)	Inferior parietal cortex volume ( 31530798) Metabolite levels ( 23823483)
Interacting Genes		21 interacting genes: ALS2CL APP APPL2 CCR10 DGKI EEA1 ERBB2 GLP1R HOXB13 HRAS INCA1 KRT15 RABAC1 RAPGEFL1 RBSN RIN2 RIN3 SGSM3 SLC27A2 TBC1D15 TBC1D17	9 interacting genes: CALCOCO1 CEP63 FIS1 OPTN RAB5A RAB5B RAB5C TAX1BP1 UBC
Entrez ID		5878	64786
HPRD ID		04947	15470
Ensembl ID		ENSG00000108774	ENSG00000121749
Uniprot IDs		A0A024R1U4 P51148	A8K8E1 Q8TC07
PDB IDs		4KYI
Enriched GO Terms of Interacting Partners?
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