RAB1A and RFK

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RAB1A	RFK
Description		RAB1A, member RAS oncogene family	riboflavin kinase
Image
GO Annotations	Cellular Component	Golgi Membrane Early Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Endomembrane System Transport Vesicle Membrane Melanosome Extracellular Exosome	Cytoplasm Mitochondrion Cytosol
	Molecular Function	GTPase Activity G Protein Activity Protein Binding GTP Binding Cadherin Binding	Protein Binding ATP Binding Riboflavin Kinase Activity Metal Ion Binding
	Biological Process	Autophagosome Assembly Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endocytosis Autophagy Golgi Organization Vesicle-mediated Transport Cell Migration Virion Assembly Growth Hormone Secretion Melanosome Transport Positive Regulation Of Interleukin-8 Production Substrate Adhesion-dependent Cell Spreading Defense Response To Bacterium Vesicle Transport Along Microtubule Cilium Assembly COPII-coated Vesicle Cargo Loading Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process	Riboflavin Metabolic Process Apoptotic Process Riboflavin Biosynthetic Process FMN Biosynthetic Process Phosphorylation Positive Regulation Of NAD(P)H Oxidase Activity Reactive Oxygen Species Metabolic Process
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Vitamin B2 (riboflavin) metabolism
Drugs			Riboflavin Flavin mononucleotide
Diseases
GWAS		High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Triglyceride levels ( 32154731)	Metabolite levels ( 23823483) Multiple sclerosis (age of onset) ( 19010793)
Interacting Genes		31 interacting genes: ADCK1 CAPNS1 CDKN1A CHML CREB1 CSNK1D EBP FSCN1 GOLGA2 GOLGA5 GORASP2 HIVEP1 MAPRE3 MICAL1 MICALL1 OCRL PSMD7 RABAC1 RABEP1 RABGGTA RABGGTB RABIF RFK RUSC2 SLC16A8 SNRNP27 SNRPG SYT5 TBC1D17 USO1 ZNF593	5 interacting genes: CNTLN CREBBP DNAJB9 RAB1A SIL1
Entrez ID		5861	55312
HPRD ID		01538	17969
Ensembl ID		ENSG00000138069	ENSG00000135002
Uniprot IDs		B7Z8M7 P62820 Q5U0I6	B2RDZ2 Q969G6
PDB IDs		2FOL 2WWX 3L0I 3SFV 3TKL 4FMB 4FMC 4FMD 4FME 4IRU 4JVS	1NB0 1NB9 1P4M 1Q9S
Enriched GO Terms of Interacting Partners?
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