BCAT1 and ENKD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		BCAT1	ENKD1
Description		branched chain amino acid transaminase 1	enkurin domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol	Cytoplasmic Microtubule Microtubule Cytoskeleton Ciliary Base
	Molecular Function	Branched-chain-amino-acid Transaminase Activity Identical Protein Binding L-leucine:2-oxoglutarate Aminotransferase Activity L-leucine Transaminase Activity L-valine Transaminase Activity L-isoleucine Transaminase Activity	Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Branched-chain Amino Acid Biosynthetic Process Leucine Biosynthetic Process Valine Biosynthetic Process
Pathways		Branched-chain amino acid catabolism
Drugs		Pyridoxal phosphate Glutamic acid Leucine Valine Isoleucine N'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE
Diseases
GWAS		Adventurousness ( 30643258) Atrial fibrillation ( 29892015) Body size at age 10 ( 32376654) Breast cancer ( 31757997) Calcium levels ( 25972035) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Erythrocyte cadmium concentration ( 27005419) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Major depressive disorder x sex interaction ( 34099189) PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia ( 30450575) PR interval ( 30679814 32439900) Pulse pressure ( 30224653) Response to statin therapy ( 20339536) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Uterine fibroid size (maximum volume) ( 30196971)	Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		8 interacting genes: C17orf75 ENKD1 KDM1A PRMT6 SMAD5 SOX5 TRIM55 TRIM63	207 interacting genes: ABI1 ABI2 ACOT7 AKAP8L ANKRD23 ANKRD49 APP ARMC5 ASB3 AVPI1 BANP BCAS2 BCAS4 BCAT1 BEGAIN BEX3 BHLHB9 BLZF1 BRAT1 C18orf54 C19orf54 C1orf105 CALCOCO1 CALCOCO2 CBY1 CBY2 CCDC102B CCDC13 CCDC136 CCDC28B CCDC85B CDCA4 CDPF1 CDR2 CDSN CEP55 CEP70 CHCHD3 CHRDL2 COA7 CTBP2 CYSRT1 DGCR6 DVL2 DVL3 DYDC1 ECM1 EFHC2 EIF4G1 EYA2 EZHIP FAM102A FAM228A FAM90A1 FCHSD2 FKBP6 FOS FOSB FSD2 GADD45G GADD45GIP1 GET4 GFAP GIGYF1 GOLGA2 GOLGA6A GOLGA6L9 GRHL3 GRIPAP1 HMBOX1 HNRNPH1 HOMEZ HOOK2 HOXA1 HSF2BP HSPB2 HSPB2-C11orf52 ID2 IGF1 IGFBP6 IKBKG IKZF3 JAKMIP1 KIFC3 KLHL20 KLHL26 KRT14 KRT15 KRT31 KRT35 KRT40 KRTAP10-5 KRTAP10-8 KRTAP11-1 KRTAP12-1 KRTAP13-2 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP4-11 KRTAP5-9 KRTAP6-2 LDOC1 LHX3 LIN7B LMO2 LRRC61 LZTS1 MAPK9 MATN4 MDFI MEIS3 MESD METTL27 MID2 MIF4GD MIPOL1 MISP MKRN3 MLH1 MORN3 MORN5 MRNIP MRPL28 MRPL38 MTUS2 MYF5 MYOZ3 N4BP3 NAB2 NBPF22P NBPF6 NCKIPSD NDUFB7 NEFL NFKBIA NHLRC4 NUTM1 OOEP PAK5 PDLIM7 PDZD4 PHC2 PIBF1 PICK1 PIK3R3 PKNOX2 PLSCR1 PNMA1 PNMA2 POLR3C PPP1CC PPP2R3C PRDM14 PRDM6 RAD54B RBCK1 RBM11 RBPMS RCN1 RUBCN RUNDC3A SLC15A2 SNRNP48 SORBS3 SPAG5 SPDEF SPSB3 SRGAP3 SSC4D STAC3 STXBP4 TENT5B TNNI1 TNS2 TOX2 TRAF1 TRAF2 TRAK1 TRGV7 TRIM23 TRIM27 TRIM35 TRIM54 TSC1 TSC22D4 TSEN15 UBXN11 USH1C USH1G USHBP1 USP20 VBP1 VPS37B VWC2 WDR62 WWOX YWHAE ZBTB14 ZC2HC1C ZFP90 ZNF143 ZNF426 ZNF511 ZNF581 ZNF76 ZRANB1
Entrez ID		586	84080
HPRD ID		00216	13151
Ensembl ID		ENSG00000060982	ENSG00000124074
Uniprot IDs		A0A024RAV0 P54687	Q9H0I2
PDB IDs		2ABJ 2COG 2COI 2COJ
Enriched GO Terms of Interacting Partners?
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