PYGB and PYGL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PYGB	PYGL
Description		glycogen phosphorylase B	glycogen phosphorylase L
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Membrane Azurophil Granule Lumen Extracellular Exosome	Extracellular Region Cytoplasm Cytosol Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Glycogen Phosphorylase Activity Pyridoxal Phosphate Binding Linear Malto-oligosaccharide Phosphorylase Activity SHG Alpha-glucan Phosphorylase Activity	Purine Nucleobase Binding Protein Binding ATP Binding Glucose Binding Glycogen Phosphorylase Activity AMP Binding Vitamin Binding Pyridoxal Phosphate Binding Bile Acid Binding Identical Protein Binding Linear Malto-oligosaccharide Phosphorylase Activity SHG Alpha-glucan Phosphorylase Activity
	Biological Process	Glycogen Catabolic Process	Glycogen Metabolic Process Glycogen Catabolic Process 5-phosphoribose 1-diphosphate Biosynthetic Process Response To Bacterium Glucose Homeostasis Necroptotic Process
Pathways		Neutrophil degranulation Glycogen breakdown (glycogenolysis)	Neutrophil degranulation Glycogen breakdown (glycogenolysis)
Drugs		Pyridoxal phosphate Alvocidib
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Calcium levels ( 24068962) Diisocyanate-induced asthma ( 25918132) Liver enzyme levels (alkaline phosphatase) ( 33972514 22001757) Platelet distribution width ( 32888494) Serum alkaline phosphatase levels ( 31666285) Telomere length ( 30185882) TPE interval (resting) ( 32386560)	Acute lymphoblastic leukemia (childhood) ( 23007406) Blood protein levels ( 30072576 29875488) Psychosis (atypical) ( 24132900) Rectal cancer ( 33632709)
Interacting Genes		7 interacting genes: ACTN1 CDH5 PPP1R3B PYGL PYGM SIAH1 XRN2	7 interacting genes: BAG1 HSD17B10 HSD3B7 IDH2 POLE2 PYGB PYGM
Entrez ID		5834	5836
HPRD ID		00720	01987
Ensembl ID		ENSG00000100994	ENSG00000100504
Uniprot IDs		P11216	P06737
PDB IDs		5IKO 5IKP	1EM6 1EXV 1FA9 1FC0 1L5Q 1L5R 1L5S 1L7X 1XOI 2ATI 2QLL 2ZB2 3CEH 3CEJ 3CEM 3DD1 3DDS 3DDW
Enriched GO Terms of Interacting Partners?
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