ALDH18A1 and DARS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ALDH18A1	DARS2
Description		aldehyde dehydrogenase 18 family member A1	aspartyl-tRNA synthetase 2, mitochondrial
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane	Nucleoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	RNA Binding Glutamate 5-kinase Activity Glutamate-5-semialdehyde Dehydrogenase Activity Protein Binding ATP Binding Identical Protein Binding	TRNA Binding Aspartate-tRNA Ligase Activity Protein Binding ATP Binding Protein Homodimerization Activity Aspartate-tRNA(Asn) Ligase Activity
	Biological Process	Glutamate Metabolic Process Proline Biosynthetic Process Ornithine Biosynthetic Process Phosphorylation Citrulline Biosynthetic Process L-proline Biosynthetic Process	Aspartyl-tRNA Aminoacylation TRNA Aminoacylation Mitochondrial Asparaginyl-tRNA Aminoacylation
Pathways			Mitochondrial tRNA aminoacylation
Drugs		Glutamic acid	Aspartic acid
Diseases
GWAS		Blood metabolite levels ( 24816252) Metabolite levels ( 23823483) PR interval ( 30046033 32439900) Staphylococcus aureus nasal carriage (persistent) ( 26569114)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		6 interacting genes: AGTRAP CDC42 CMTM5 COQ9 DARS2 SYCE1L	15 interacting genes: AIMP2 ALDH18A1 AOC3 CDIPT COL8A2 CYB561 DPYSL5 EPHA8 FETUB KARS1 PLP2 THSD7B TMEM239 TSPAN33 UNC50
Entrez ID		5832	55157
HPRD ID		00696	07677
Ensembl ID		ENSG00000059573	ENSG00000117593
Uniprot IDs		P54886	Q6PI48 Q9H9J7
PDB IDs		2H5G	4AH6
Enriched GO Terms of Interacting Partners?
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