PEX19 and IFNB1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PEX19	IFNB1
Description		peroxisomal biogenesis factor 19	interferon beta 1
Image
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Brush Border Membrane Protein-containing Complex	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Peroxisome Membrane Targeting Sequence Binding Peroxisome Membrane Class-1 Targeting Sequence Binding Protein N-terminus Binding ATPase Binding Protein Carrier Activity	Cytokine Activity Type I Interferon Receptor Binding Protein Binding Chloramphenicol O-acetyltransferase Activity
	Biological Process	Protein Targeting To Peroxisome Peroxisome Organization Peroxisome Fission Protein Import Into Peroxisome Membrane Protein Stabilization Chaperone-mediated Protein Folding Establishment Of Protein Localization To Peroxisome Negative Regulation Of Lipid Binding	Adaptive Immune Response T Cell Activation Involved In Immune Response B Cell Activation Involved In Immune Response Natural Killer Cell Activation Involved In Immune Response Humoral Immune Response Cell Surface Receptor Signaling Pathway Response To Virus Cytokine-mediated Signaling Pathway Natural Killer Cell Activation B Cell Differentiation Positive Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein Cellular Response To Interferon-beta B Cell Proliferation Response To Exogenous DsRNA Negative Regulation Of Viral Genome Replication Positive Regulation Of Innate Immune Response Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of T Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus Type I Interferon Signaling Pathway Cellular Response To Exogenous DsRNA Cellular Response To Virus Negative Regulation Of T-helper 2 Cell Cytokine Production Positive Regulation Of Apoptotic Signaling Pathway
Pathways		ABC transporters in lipid homeostasis Class I peroxisomal membrane protein import Class I peroxisomal membrane protein import	Oxidative Stress Induced Senescence Interferon alpha/beta signaling Regulation of IFNA signaling Regulation of IFNA signaling TRAF3-dependent IRF activation pathway TRAF6 mediated IRF7 activation Factors involved in megakaryocyte development and platelet production
Drugs			Beta-D-Glucose
Diseases
GWAS			Axial length ( 24144296)
Interacting Genes		39 interacting genes: ABCD1 ABCD2 ABCD3 BCL2L11 CDC25A CDKN2A DLG4 EIF1B F11R FKBP7 GSKIP IFNB1 IL23A IRF3 KIFAP3 MFSD5 NAT8L OIP5 PEX10 PEX11A PEX11B PEX12 PEX13 PEX14 PEX16 PEX26 PEX3 PMP22 PPIB PSORS1C2 PXMP4 SLC25A17 SLC34A1 SMAD2 SRPK1 STK3 SUOX TMEM54 TXN2	3 interacting genes: IFNAR1 IFNAR2 PEX19
Entrez ID		5824	3456
HPRD ID		02610	00972
Ensembl ID		ENSG00000162735	ENSG00000171855
Uniprot IDs		A0A0S2Z497 P40855	P01574
PDB IDs		2W85 2WL8 3AJB 3MK4 5LNF	1AU1
Enriched GO Terms of Interacting Partners?
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