PURA and MIR205

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		PURA	MIR205
Description		purine rich element binding protein A	microRNA 205
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Dendrite Cytoplasm Neuronal Cell Body Postsynapse Glutamatergic Synapse	Extracellular Space
	Molecular Function	Translation Repressor Activity, MRNA Regulatory Element Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Double-stranded Telomeric DNA Binding Single-stranded DNA Binding RNA Binding Protein Binding Purine-rich Negative Regulatory Element Binding SMAD Binding DNA-binding Transcription Factor Binding Transcription Regulator Inhibitor Activity	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Unwinding Involved In DNA Replication DNA Replication Initiation Regulation Of Transcription By RNA Polymerase II Nervous System Development Positive Regulation Of Cell Population Proliferation Negative Regulation Of Translation Cell Differentiation Negative Regulation Of DNA-binding Transcription Factor Activity Lymphocyte Proliferation Epithelial Cell Proliferation Dendritic Transport Of Messenger Ribonucleoprotein Complex	Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Inflammatory Response Negative Regulation Of Fibroblast Growth Factor Production Regulation Of Aorta Morphogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Metalloendopeptidase Activity
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971)
Interacting Genes		58 interacting genes: ADAP1 CCNT1 CDK5 E2F1 IL7R MIR1-1 MIR106B MIR122 MIR128-1 MIR128-2 MIR140 MIR143 MIR155 MIR15B MIR16-2 MIR17 MIR18B MIR199A1 MIR19A MIR19B1 MIR19B2 MIR200C MIR205 MIR20B MIR21 MIR221 MIR222 MIR25 MIR29B1 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR7-1 MIR7-2 MIR9-2 MIR92A2 MIR93 MIRLET7A1 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I OGT PTEN PURB RAF1 RB1 SP1 YBX1	92 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CELF1 CELF2 CPSF1 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 FAM98A FAM98B FIP1L1 FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 NUFIP2 PDCD11 PGAM5 PLRG1 PTBP1 PTBP3 PTCD3 PUF60 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RBM45 RBMS1 RBMS2 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYNCRIP TAF15 TRA2A TRA2B TRIM25 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZC3H7B ZNF346
Entrez ID		5813	406988
HPRD ID		02721
Ensembl ID		ENSG00000185129	ENSG00000284485
Uniprot IDs		Q00577
PDB IDs
Enriched GO Terms of Interacting Partners?
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