BAX and ERN1

  • Number of citations of the paper that reports this interaction (PubMedID 16645094)
  • 251
  • Data Source:
  • HPRD (in vitro, in vivo)

BAX

ERN1

Description BCL2 associated X, apoptosis regulator endoplasmic reticulum to nucleus signaling 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Liver enzyme levels (alkaline phosphatase) ( 33972514)
  • Liver injury in anti-retroviral drug treated HIV ( 28388302)
Interacting Genes 29 interacting genes: ANP32B BAK1 BBC3 BCL2 BCL2A1 BCL2L1 BCL2L10 BCL2L12 BCL2L2 BID ERN1 HSF2BP KCNA3 LEF1 MAP2K1 MCL1 MOAP1 NOL3 PARK7 PMAIP1 PPP1CA SFN SH3GLB1 SLC25A4 UHRF2 VDAC1 YWHAB YWHAQ ZBTB24 15 interacting genes: BAK1 BAX CEP112 COPS5 HSP90AA1 HSPA5 MAP3K5 P4HB PSEN1 SRPK2 STUB1 SYVN1 TAOK3 TNFRSF1A TRAF2
Entrez ID 581 2081
HPRD ID 02498 04943
Ensembl ID ENSG00000087088 ENSG00000178607
Uniprot IDs I6LPK7 Q07812 Q5ZPJ0 Q5ZPJ1 O75460
PDB IDs 1F16 2G5B 2K7W 2LR1 3PK1 3PL7 4BD2 4BD6 4BD7 4BD8 4BDU 4S0O 4S0P 4UF2 4ZIE 4ZIF 4ZIG 4ZIH 4ZII 5W5X 5W5Z 5W60 5W61 6EB6 6L8V 6L95 6TRR 6XY6 2HZ6 3P23 4U6R 4YZ9 4YZC 4YZD 4Z7G 4Z7H 5HGI 6HV0 6HX1 6SHC 6URC 6W39 6W3A 6W3B 6W3C 6W3E 6W3K
Enriched GO Terms of Interacting Partners?
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