PTPRH and DHPS

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		PTPRH	DHPS
Description		protein tyrosine phosphatase receptor type H	deoxyhypusine synthase
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Integral Component Of Plasma Membrane Apical Plasma Membrane Microvillus Membrane	Cytoplasm Cytosol
	Molecular Function	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding Cadherin Binding	Protein Binding Deoxyhypusine Synthase Activity Identical Protein Binding
	Biological Process	Protein Dephosphorylation Apoptotic Process Peptidyl-tyrosine Dephosphorylation Involved In Inactivation Of Protein Kinase Activity	Translation Spermidine Metabolic Process Positive Regulation Of Cell Population Proliferation Peptidyl-lysine Modification To Peptidyl-hypusine
Pathways			Hypusine synthesis from eIF5A-lysine
Drugs			1-Guanidinium-7-Aminoheptane
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Serum metabolite levels ( 33031748) Systemic lupus erythematosus ( 28714469)	Platelet distribution width ( 32888494)
Interacting Genes		16 interacting genes: BCAR1 CRK DHPS DOK1 EGFR ERBB3 ERBB4 GHR KRTAP10-3 KRTAP10-8 LAIR1 LCK MAPK1 MLH1 PTK2 PXN	17 interacting genes: BRCA1 EIF5A EIF5A2 LNX1 MEOX2 NIF3L1 NTAQ1 NUDT18 PAX6 PTPRH RAB27B RBP1 REL RPL9 UPF1 VASH1 ZNF138
Entrez ID		5794	1725
HPRD ID		03942	02969
Ensembl ID		ENSG00000080031	ENSG00000095059
Uniprot IDs		Q9HD43	A0A024R7D0 A0A024R7E9 P49366
PDB IDs			1DHS 1RLZ 1ROZ 1RQD 6P4V 6PGR 6WKZ 6WL6 6XXH 6XXI 6XXJ 6XXK 6XXL 6XXM
Enriched GO Terms of Interacting Partners?
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