PTPN13 and ARHGAP29

Number of citations of the paper that reports this interaction (PubMedID 9305890)
41

Data Source:
HPRD (in vitro)

		PTPN13	ARHGAP29
Description		protein tyrosine phosphatase non-receptor type 13	Rho GTPase activating protein 29
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Lamellipodium Neuron Projection Cell Body Extracellular Exosome	Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Phosphatidylinositol 3-kinase Regulatory Subunit Binding	GTPase Activator Activity PDZ Domain Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Protein Phosphorylation Protein Dephosphorylation Regulation Of Phosphatidylinositol 3-kinase Signaling Peptidyl-tyrosine Dephosphorylation	Rho Protein Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Activation Of GTPase Activity
Pathways		Synthesis of PIPs at the plasma membrane Interleukin-37 signaling RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle	RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Eyebrow thickness ( 26926045) Hemoglobin levels ( 32327693) Kidney disease (end stage renal disease vs non-end stage renal disease) in type 1 diabetes ( 27647854) Kidney disease (end stage renal disease vs normoalbuminuria) in type 1 diabetes ( 27647854) Tinnitus ( 33742053) Word spelling ( 30741946)	Aspartate aminotransferase levels ( 33547301) Cleft lip with or without cleft palate ( 28054174) D-dimer levels ( 21502573) Orofacial clefts ( 28054174) Plateletcrit ( 32888494) Systolic blood pressure ( 30224653)
Interacting Genes		24 interacting genes: APC ARHGAP29 BEX3 BRD7 CRHR1 CRIP2 CTNNB1 EFNB1 EFNB2 FADD FAS FASLG GHR MTNR1A NFKBIA NGFR PDLIM4 PKN2 PLEKHA1 PLEKHA2 PRKACA RAPGEF6 TRIP6 YWHAZ	7 interacting genes: HRAS KDM1A MAGEA11 PTPN13 RAP2A RHOA TRIM54
Entrez ID		5783	9411
HPRD ID		02602	06674
Ensembl ID		ENSG00000163629	ENSG00000137962
Uniprot IDs		Q12923	Q52LW3
PDB IDs		1D5G 1Q7X 1WCH 2M0Z 2M10 3LNX 3LNY 3PDZ 5GLJ
Enriched GO Terms of Interacting Partners?
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