PTPN7 and PTK7

Number of citations of the paper that reports this interaction (PubMedID 28065597)
37

Data Source:
BioGRID (two hybrid)

		PTPN7	PTK7
Description		protein tyrosine phosphatase non-receptor type 7	protein tyrosine kinase 7 (inactive)
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Cytoplasmic Side Of Plasma Membrane Microtubule Cytoskeleton Mitotic Spindle	Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion
	Molecular Function	Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding	Protein Kinase Activity Protein Binding ATP Binding Cell Adhesion Molecule Binding Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway
	Biological Process	MAPK Cascade Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation	Establishment Of Planar Polarity Kidney Development Ventricular Septum Development Axis Elongation Protein Phosphorylation Cell Adhesion Signal Transduction Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Reorganization Wound Healing Establishment Of Epithelial Cell Apical/basal Polarity Convergent Extension Lung-associated Mesenchyme Development Regulation Of Canonical Wnt Signaling Pathway Coronary Vasculature Development Cellular Response To Retinoic Acid Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways		Negative regulation of MAPK pathway Interleukin-37 signaling
Drugs
Diseases
GWAS		Basophil percentage of white cells ( 32888494) Breast cancer ( 23535733) Mean spheric corpuscular volume ( 32888494) Plateletcrit ( 32888494)	Coronary artery disease ( 29212778)
Interacting Genes		17 interacting genes: AATK APP CCDC57 EGFR EPHA2 ERBB3 ERBB4 GMCL1 IGF1R MAPK1 MAPK14 MAPK3 PPP1CA PRKACA PTK7 ROR2 SIRPA	48 interacting genes: BYSL CDC14A CDKN1A CLIC5 CLNK CTDSP2 DUSP10 DUSP14 DUSP15 DUSP18 DUSP19 DUSP21 DUSP26 DUSP29 ENPP5 ERBB2 ILKAP KRTAP1-3 KRTAP10-8 MDFI MTMR1 MTMR10 MTMR6 MTMR9 MTUS2 NBPF19 NOTCH2NLA PPM1A PPM1B PPM1F PPM1K PPP3CA PPP3CB PSMB9 PTEN PTPN11 PTPN12 PTPN6 PTPN7 PTPRR RPS2 RTN4R STYX TNFRSF21 TPTE TPTE2 TRAM2 VGLL1
Entrez ID		5778	5754
HPRD ID		01480	03534
Ensembl ID		ENSG00000143851	ENSG00000112655
Uniprot IDs		A0A024R9A7 B4DZD9 P35236	Q13308
PDB IDs		1ZC0 2A3K 2GP0 2GPH 2HVL 2QDC 2QDM 2QDP 3D42 3D44 3O4S 3O4T 3O4U	6VG3
Enriched GO Terms of Interacting Partners?
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