NCOA5 and HTATIP2

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, pull down)
HPRD (in vitro)

		NCOA5	HTATIP2
Description		nuclear receptor coactivator 5	HIV-1 Tat interactive protein 2
Image
GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Actin Cytoskeleton	Nucleus Nuclear Envelope Cytoplasm Cytosol Membrane
	Molecular Function	Chromatin Binding Transcription Corepressor Activity RNA Binding Protein Binding	Transcription Coactivator Activity Protein Serine/threonine Kinase Activity Protein Binding Oxidoreductase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Glucose Homeostasis Negative Regulation Of Insulin Receptor Signaling Pathway	Angiogenesis Regulation Of Transcription By RNA Polymerase II Apoptotic Process Cell Differentiation Negative Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Angiogenesis Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation Import Into Nucleus
Pathways
Drugs		17alpha-Estriol	Polyethylene glycol 400
Diseases
GWAS		Crohn's disease ( 28067908) Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831) Follicular lymphoma or multiple sclerosis ( 31407831) HDL cholesterol levels ( 32203549) Hodgkin's lymphoma ( 30194254) Inflammatory bowel disease ( 28067908) Marginal zone lymphoma or multiple sclerosis ( 31407831) Multiple sclerosis ( 31604244 21833088) Systemic lupus erythematosus ( 28714469) Tonsillectomy ( 27182965 28928442)	Bell's palsy ( 33602968) Fractional shortening ( 29403010) Obesity-related traits ( 23251661) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762)
Interacting Genes		19 interacting genes: ACOT7 CCDC57 CDC37 FAM214B GORASP2 HTATIP2 KANK2 KHDRBS2 KHDRBS3 MEIG1 NR1D2 NTAQ1 PICK1 RAB30 SYT16 TSC22D1 TSGA10IP UBL5 ZNF326	25 interacting genes: ABHD4 ACSL4 AQP6 ASF1A EHHADH ETS1 FAM209A FITM2 GET1 HDAC6 HSD17B11 JAGN1 JPH1 MIEF1 MTIF3 NCOA5 PITPNC1 PLIN2 RAB5A REEP4 RETREG3 SH3GLB1 SLC10A6 TMEM115 TMX2
Entrez ID		57727	10553
HPRD ID		14813	09288
Ensembl ID		ENSG00000124160	ENSG00000109854
Uniprot IDs		Q9HCD5	Q9BUP3
PDB IDs		1V95 2J7X 2J7Y 4ZI1	2BKA
Enriched GO Terms of Interacting Partners?
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