NYAP2 and PIK3R1

  • Number of citations of the paper that reports this interaction (PubMedID 21946561)
  • 21

NYAP2

PIK3R1

Description neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 phosphoinositide-3-kinase regulatory subunit 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase levels ( 33547301)
  • Angiotensin-converting enzyme inhibitor intolerance ( 28030426)
  • Aspartate aminotransferase levels ( 33547301)
  • Cortical volume ( 32963231)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • HDL cholesterol levels ( 32203549)
  • Insulin levels in response to oral glucose tolerance test (fasting) ( 29093273)
  • LDL cholesterol levels in HIV infection ( 33109212)
  • Menopause (age at onset) ( 23307926)
  • Modified Stumvoll Insulin Sensitivity Index (BMI interaction) ( 27416945)
  • Modified Stumvoll Insulin Sensitivity Index (model adjusted for BMI) ( 27416945)
  • Myocardial infarction ( 33532862)
  • Neurociticism ( 29500382)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Squamous cell lung carcinoma ( 28604730)
  • Triglyceride levels in HIV infection ( 33109212)
  • Urinary albumin excretion (no hypertensive medication) ( 30220432)
  • Urinary albumin-to-creatinine ratio ( 31630189 30910378)
  • Walking pace ( 33128006)
Interacting Genes 6 interacting genes: AGFG1 CYFIP1 MORN4 NCKAP1 PIK3R1 WASF1 176 interacting genes: ABL1 ADAM12 ADAMTS2 AGAP2 AKT1 ALK ANK3 APPL1 AR ARAF ARHGAP1 ARHGAP17 ARHGAP32 AXL BCAR1 BLK BRCA1 CBL CBLB CCL14 CD19 CD22 CD28 CD2AP CD3E CD4 CD40 CD5 CD7 CDC42 CDH2 CHRNA7 CIP2A CLNK CRK CRKL CSF1R CSF2RA CTLA4 CTNNB1 CXCL2 CYP4A11 DLX2 DNM1 DOK1 EGF EGFR ENKUR EPHA2 EPOR ERAS ERBB2 ERBB3 ERBB4 ESR1 EZR FASLG FCGR2A FER FES FGFR1 FLT1 FYN GAB1 GAB2 GAB3 GHR GP1BA GRB2 GSPT1 GTF2H1 HCK HCST HGS HOXA1 HRAS HTT IFNAR1 IGF1R IKZF3 IL13 IL1R1 IL1RAP IL2RB IL7R INPP4A INSR IRS1 IRS2 IRS4 ITSN1 JAK1 JAK2 JAK3 KBTBD2 KHDRBS1 KIT LAT LCK LNX2 LRRK2 MAPK8 MAPT MET MME MST1R MYO16 NFKBIA NTRK1 NTRK2 NUP85 NYAP1 NYAP2 PASK PDE4D PDGFB PDGFRA PDGFRB PECAM1 PFN1 PIK3AP1 PIK3CA PIK3CB PIK3CD PPM1A PRMT8 PROM1 PSEN1 PSMB5 PTK2 PTK2B PTPN11 PTPN6 RAC1 RASA1 RASD2 RB1 RET RRAS2 SH3KBP1 SHB SHC1 SLC9A2 SOCS1 SOCS6 SOCS7 SQSTM1 SRC SSTR2 STAT3 SYK SYN1 TEC TEK TGFBR1 TGFBR2 TIE1 TLR2 TNS4 TOM1L1 TRAT1 TSHR TTR TUB TUBA1B TUBG1 TXK TYK2 TYRO3 VAV1 VAV3 WAS WASF3 WBP11 YWHAG YWHAZ
Entrez ID 57624 5295
HPRD ID 13867 01381
Ensembl ID ENSG00000144460 ENSG00000145675
Uniprot IDs Q9P242 A0A2X0SFG1 P27986
PDB IDs 1A0N 1AZG 1H9O 1PBW 1PHT 1PIC 1PKS 1PKT 2IUG 2IUH 2IUI 2RD0 2V1Y 3HHM 3HIZ 3I5R 3I5S 4A55 4JPS 4L1B 4L23 4L2Y 4OVU 4OVV 4WAF 4YKN 4ZOP 5AUL 5FI4 5GJI 5ITD 5M6U 5SW8 5SWG 5SWO 5SWP 5SWR 5SWT 5SX8 5SX9 5SXA 5SXB 5SXC 5SXD 5SXE 5SXF 5SXI 5SXJ 5SXK 5UBT 5UK8 5UKJ 5UL1 5VLR 5XGH 5XGI 5XGJ 6NCT 6PYR 6PYU 7CIO
Enriched GO Terms of Interacting Partners?
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