ISY1 and XAB2

Number of citations of the paper that reports this interaction (PubMedID 26344197)
178

Data Source:
BioGRID (biochemical, two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology)

		ISY1	XAB2
Description		ISY1 splicing factor homolog	XPA binding protein 2
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GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm U2-type Catalytic Step 1 Spliceosome Catalytic Step 2 Spliceosome Post-mRNA Release Spliceosomal Complex Post-spliceosomal Complex	Prp19 Complex Nucleus Nucleoplasm Membrane Intracellular Membrane-bounded Organelle U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Post-mRNA Release Spliceosomal Complex
	Molecular Function	RNA Binding Protein Binding	Protein Binding
	Biological Process	Generation Of Catalytic Spliceosome For Second Transesterification Step MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome	Generation Of Catalytic Spliceosome For First Transesterification Step MRNA Splicing, Via Spliceosome Blastocyst Development Transcription-coupled Nucleotide-excision Repair Transcription, DNA-templated Cerebral Cortex Development
Pathways		Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER mRNA Splicing - Major Pathway	Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		11 interacting genes: ACAD9 CCNC EXOC8 FAM90A1 KDM8 LMO1 LMO2 MLH1 PLXND1 WBP4 XAB2	17 interacting genes: CACHD1 DHX16 ERCC6 ERCC8 GLIS2 ILF3 ISY1 MIR106B MIR34B MIRLET7E MIRLET7G MIRLET7I POLR2A PPIE SMAD9 SUMO2 XPA
Entrez ID		57461	56949
HPRD ID		13834	18306
Ensembl ID		ENSG00000240682	ENSG00000076924
Uniprot IDs		Q9ULR0	Q9HCS7
PDB IDs		5YZG 6FF7 6ZYM 7A5P	5MQF 5XJC 5YZG 5Z56 5Z57 6FF7 6ICZ 6ID0 6ID1 6QDV 7A5P 7ABI
Enriched GO Terms of Interacting Partners?
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