REXO1 and RLIM

Number of citations of the paper that reports this interaction (PubMedID 22596162)
86

Data Source:
BioGRID (enzymatic study)

		REXO1	RLIM
Description		RNA exonuclease 1 homolog	ring finger protein, LIM domain interacting
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body	Nucleus Nucleoplasm Cytoplasm Cytosol Transcription Repressor Complex
	Molecular Function	Nucleic Acid Binding Exonuclease Activity	Transcription Corepressor Activity Ubiquitin-protein Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Nucleic Acid Phosphodiester Bond Hydrolysis	Negative Regulation Of Transcription By RNA Polymerase II Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Random Inactivation Of X Chromosome Regulation Of Dosage Compensation By Inactivation Of X Chromosome
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Body mass index ( 29273807) Essential hypertension (time to event) ( 32589924) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Brain asymmetrical skew (horizontal) ( 33836062)
Interacting Genes		4 interacting genes: ELOA PAFAH1B2 RLIM TCEA1	29 interacting genes: BRF1 ESR1 ISL1 LDB1 LDB2 LHX1 LHX2 LHX3 LIMK1 LMO2 LNX2 MDM2 PDLIM1 REXO1 RPS14 SIN3A SMAD7 SMURF2 SNX17 SS18L1 STAT6 TERF1 TNFAIP3 UBC UBE2D1 UBE2D3 UBE2D4 UBE2E1 UBE2K
Entrez ID		57455	51132
HPRD ID		15478	02304
Ensembl ID		ENSG00000079313	ENSG00000131263
Uniprot IDs		Q8N1G1	Q9NVW2
PDB IDs			6W7Z 6W9A 6W9D
Enriched GO Terms of Interacting Partners?
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