PBXIP1 and ZMYND8

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		PBXIP1	ZMYND8
Description		PBX homeobox interacting protein 1	zinc finger MYND-type containing 8
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex Cytosol Microtubule Membrane	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Dendritic Spine Dendritic Shaft
	Molecular Function	DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Transcription Corepressor Activity Protein Binding	Transcription Corepressor Activity Protein Binding Zinc Ion Binding Protein Domain Specific Binding Methylated Histone Binding Protein N-terminus Binding Lysine-acetylated Histone Binding DNA-binding Transcription Factor Binding
	Biological Process	Production Of Molecular Mediator Involved In Inflammatory Response Cell Adhesion Multicellular Organism Development Cell Migration Extracellular Matrix Disassembly Cell Differentiation Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Articular Cartilage Development Histone H3-K56 Acetylation Gene Expression Involved In Extracellular Matrix Organization Positive Regulation Of Chondrocyte Proliferation Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity	Negative Regulation Of Cell Migration Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Filopodium Assembly Positive Regulation Of Dendritic Spine Development Modulation Of Excitatory Postsynaptic Potential Regulation Of Postsynaptic Density Protein 95 Clustering Positive Regulation Of Dendritic Spine Maintenance
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Inflammatory bowel disease ( 27569725) Prostate cancer ( 23535732)	Bipolar disorder ( 34099189) Caffeine consumption from coffee ( 33287642) Daytime nap ( 33568662) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Mean platelet volume ( 32888494 27863252) Metabolite levels ( 23823483) Migraine ( 27182965) Parahippocampal gyrus volume ( 31530798) Platelet distribution width ( 32888494) Response to protease inhibitor treatment in hepatitis c (bilirubin toxicity) ( 24503447) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		28 interacting genes: BRPF1 CAMLG CAPN2 CCDC85B CCNC DAXX DEF6 DPPA2 ESR1 GABARAPL1 GMCL1 GRB2 KRTAP10-6 LCA5L MDFI MDM2 MORF4L1 PCBD2 PPTC7 PRKAA2 SGTA TRAF7 TSNAX UBQLN1 UBQLN4 WASHC3 ZMYND8 ZZZ3	17 interacting genes: ATN1 ATRX CSNK1E ERBB2 FHOD1 FMR1 FXR2 H3C1 MEOX2 PBXIP1 PRKCB RERE SPOP SUMO2 USP7 ZBTB7A ZFYVE9
Entrez ID		57326	23613
HPRD ID		17823	10166
Ensembl ID		ENSG00000163346	ENSG00000101040
Uniprot IDs		B4E0K4 Q96AQ6	A0A087WVZ6 A6H8Y8 Q2HXV5 Q569J9 Q9ULU4
PDB IDs			4COS 5B73 5MQ4 5Y1Z
Enriched GO Terms of Interacting Partners?
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