ADAMTSL3 and ALPK3

		ADAMTSL3	ALPK3
Description		ADAMTS like 3	alpha kinase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix Intracellular Membrane-bounded Organelle	Nucleus
	Molecular Function	Metalloendopeptidase Activity Protein Binding	ATP Binding Protein Serine Kinase Activity
	Biological Process	Extracellular Matrix Organization	Protein Phosphorylation Heart Development Cardiac Muscle Cell Development
Pathways		Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Appendicular lean mass ( 28724990) Asthma ( 34103634 32296059) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder lithium response (categorical) or schizophrenia ( 29121268) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body shape index ( 34021172) Body size at age 10 ( 32376654) Childhood body mass index ( 33045005) Chronic obstructive pulmonary disease ( 30804561 33909500) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Height ( 21998595 28552196 20881960 25282103 25429064 19343178 23563607 31562340 18391950 18391951 18391952 20397748 33713608 20189936) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 28552196 34021172 25673412) Hip index ( 34021172) Lean body mass ( 28724990) Optic disc size ( 31809533) Pulse pressure ( 30224653) Schizophrenia ( 28991256 25056061 29483656 30285260) Spine bone size ( 31053729) Waist circumference ( 26785701) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 28552196 34021172 26785701 25673412 28448500) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Adverse response to chemotherapy (neutropenia/leucopenia) (gemcitabine) ( 23648065) Alzheimer's disease (age of onset) ( 22005931) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Hip circumference adjusted for BMI ( 34021172) Hypertrophic cardiomyopathy (sarcomere negative) ( 33495597) Left ventricle wall thickness ( 33495596) Left ventricular end-systolic volume ( 33495596) Left ventricular global circumferential strain ( 33495596) Left ventricular mass to end-diastolic volume ratio ( 33495596) Metabolite levels ( 23823483) P wave terminal force ( 28794112) PR interval ( 32439900) Schizophrenia ( 29483656)
Interacting Genes		21 interacting genes: ALPK3 BNC1 CYSRT1 EFL1 GLRX3 GOLGA2P10 HDGFL3 IDH3A KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-6 KRTAP10-8 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP5-7 MDFI NOTCH2NLA RAMAC	2 interacting genes: ADAMTSL3 CPEB1
Entrez ID		57188	57538
HPRD ID		12426	11365
Ensembl ID		ENSG00000156218	ENSG00000136383
Uniprot IDs		P82987	Q96L96
PDB IDs
Enriched GO Terms of Interacting Partners?
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