PELI2 and TIMM9

		PELI2	TIMM9
Description		pellino E3 ubiquitin protein ligase family member 2	translocase of inner mitochondrial membrane 9
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GO Annotations	Cellular Component	Cytosol	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Mitochondrial Intermembrane Space Protein Transporter Complex
	Molecular Function	Protein Binding Ubiquitin-ubiquitin Ligase Activity Ubiquitin Protein Ligase Activity	Protein Binding Zinc Ion Binding Membrane Insertase Activity Protein Homodimerization Activity Chaperone Binding
	Biological Process	Protein Polyubiquitination Positive Regulation Of Protein Phosphorylation Toll Signaling Pathway Regulation Of Toll Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAPK Cascade	Protein Targeting To Mitochondrion Sensory Perception Of Sound Protein Insertion Into Mitochondrial Inner Membrane
Pathways		Interleukin-1 signaling IRAK1 recruits IKK complex IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	Mitochondrial protein import Mitochondrial protein import
Drugs
Diseases
GWAS		Adverse response to chemotherapy (amenorrhea) in breast cancer ( 31371054) Body mass index (smoking years interaction) ( 23192594) Body mass index (ever vs never smoking interaction) ( 23192594) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) End-stage kidney disease ( 31178898) Height ( 25133637) Nickel levels ( 26025379) Telomere length ( 21460395)	Brain morphology (MOSTest) ( 32665545)
Interacting Genes		35 interacting genes: BCL10 CLEC17A CREB3L3 DEAF1 ERO1A FN1 FRYL HNRNPK HYAL2 IRAK1 IRAK2 IRAK4 LAMC3 LTBP3 LZTFL1 MDFI MEOX1 MYD88 NUP62 OR7D2 PCGF2 PICALM RABEP1 REL RMDN3 SEPTIN3 SP4 SRPK1 THAP7 TIMM9 TMEM79 TP53 TP63 TRIM32 UBQLN4	2 interacting genes: MGAT2 PELI2
Entrez ID		57161	26520
HPRD ID		17835	09574
Ensembl ID		ENSG00000139946	ENSG00000100575
Uniprot IDs		Q9H716 Q9HAT8	A0A024R648 A0A1W2PQS5 A0A1W2PRH9 G3V502 Q9Y5J7
PDB IDs		3EGA 3EGB	2BSK 7CGP
Enriched GO Terms of Interacting Partners?
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